{"title":"Tuberous Sclerosis Complex with Diffuse Cytomegalovirus Fetal Infection: Case Report and Review of the Literature","authors":"N. Jin, S. Shuja, C. Monteiro, R. Makary","doi":"10.5580/4b1","DOIUrl":null,"url":null,"abstract":"We report a case of a stillborn female fetus with combined stigmata of Tuberous Sclerosis Complex (TSC) and cytomegalovirus (CMV) infection. The baby was premature and small for gestational age (1625g). The heart showed multiple cardiac rhabdomyomas. The brain showed cortical tubers and subependymal nodule. Renal cysts are present. Autopsy also revealed multiple organ infected by CMV including lungs, liver and kidneys. The mother was 24 year old. The placental gross findings show multiple hematoma and infarction on maternal side, acute chorionitis with cytomegalovirus infection, chronic deciduitis and focal chronic villitis, might be the cause of the intrauterine demise of the fetus","PeriodicalId":75037,"journal":{"name":"The Internet journal of pediatrics and neonatology","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2009-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"The Internet journal of pediatrics and neonatology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.5580/4b1","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
We report a case of a stillborn female fetus with combined stigmata of Tuberous Sclerosis Complex (TSC) and cytomegalovirus (CMV) infection. The baby was premature and small for gestational age (1625g). The heart showed multiple cardiac rhabdomyomas. The brain showed cortical tubers and subependymal nodule. Renal cysts are present. Autopsy also revealed multiple organ infected by CMV including lungs, liver and kidneys. The mother was 24 year old. The placental gross findings show multiple hematoma and infarction on maternal side, acute chorionitis with cytomegalovirus infection, chronic deciduitis and focal chronic villitis, might be the cause of the intrauterine demise of the fetus
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