Obstetric and Neonatal Outcomes in Congenital Isolated Cardiac Anomalies - Single Center Experience

FORBES Pub Date : 2020-01-01 DOI:10.5222/forbes.2020.39974
E. Çağlıyan, S. Ozmen, S. Demir, Aslı Akdöner, S. Altunyurt, B. Deliloğlu, K. Yıldız, se Seynep Genç Hal, M. Kır
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Abstract

Objective: Evidence shows that rather than postnatal diagnoses, prenatal diagnoses of congenital heart diseases are correlated with better long-term results and lower mortality rates. In this retrospective study, neonatal stage results of infants with isolated cardiac anomalies, their indications for operation or intervention (if any), and the mortality rates in the first age are attempted to be demonstrated. Method: The study was conducted through the retrospective analysis of 47 patients who were diagnosed with fetal cardiac anomaly in the antenatal period, and monitored during natal and postnatal stages at the same center in the Departments of Obstetrics and Gynecology and Pediatric Cardiology of Dokuz Eylul University Hospital. Results: In our center 36 patients gave birth by cesarean section, and 11 patients by spontaneous vaginal delivery. Two low birthweight neonates were born (<2500 g), and these neonates were observed to have hypoplastic left heart and Fallot tetralogy. Thirty-nine of the 47 neonates born with isolated cardiac anomaly were operated after birth. Five patients were advised follow-ups. The remaining 3 neonates died within 48 hours after birth. Survival rate of the operated neonates was 59.5% and the general survival rate was 59.5%. Average 1, and 5-minute APGAR scores of the infants were 7.8 (3-9) and 9.0 (8-10), respectively The neonates were operated an average of 3 days after birth, and the average duration hospitalization of neonates were 12 days. Twentynine neonates needed preoperative respiratory support and 37 of them received prostaglandin E1 infusion. Follow-up was advised for 3 neonates within the first month and the first year. Five neonates needed operation during the specified period, and 2 neonates died. Conclusion: In conclusion, prenatal diagnosis of congenital heart diseases allows planning the delivery in tertiary care centers, stabilization of the infants in the preoperative period and realization of emergency intervention.
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先天性孤立性心脏异常的产科和新生儿结局-单中心经验
目的:有证据表明,先天性心脏病的产前诊断与较好的远期疗效和较低的死亡率相关,而不是产后诊断。在这项回顾性研究中,新生儿阶段的结果孤立的心脏异常的婴儿,其手术或干预的指征(如果有的话),并在第一年龄的死亡率试图证明。方法:回顾性分析Dokuz Eylul大学附属医院妇产科和小儿心脏科同一中心诊断为胎儿心脏异常的47例患者,并对其进行产前和产后监测。结果:本组患者剖宫产36例,顺产11例。2例低出生体重新生儿(<2500 g),观察到这些新生儿有左心发育不全和法洛四联症。47例孤立性心脏异常新生儿中有39例在出生后进行了手术。5例患者建议随访。其余3例新生儿在出生后48小时内死亡。术后新生儿生存率为59.5%,总生存率为59.5%。新生儿平均1分钟、5分钟APGAR评分分别为7.8分(3-9分)和9.0分(8-10分),新生儿平均在出生后3天手术,平均住院时间为12天。29例新生儿术前需要呼吸支持,其中37例给予前列腺素E1输注。建议对3名新生儿在第一个月和第一年进行随访。5例患儿在规定时间内需要手术,2例患儿死亡。结论:先天性心脏病的产前诊断有助于在三级保健中心计划分娩,在术前稳定婴儿并实现紧急干预。
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FORBES
FORBES BUSINESS, FINANCE-
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