Study of the Antitumor Activity of Selenium Nanoparticles

Arina Romanovna Maslyakova, Sabina Arturovna Magomedova, Islam Nazirovich Romantsov, Sharip Magomedrasulovich Nurbagandov, Mikhail Nikolaevich Bulovin, Oleg Rodionoviсh Podobin
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Abstract

In the scientific literature, studies on the feasibility of using selenium nanoparticles in the development of pharmaceuticals are widely presented. The positive effects of selenium in the treatment of cancer, hepatitis C, thyroid disease, cardiovascular disease, asthma, and other diseases have been studied. This scientific paper presents the results of studies on the effect of selenium nanoparticles on the development of a cancerous tumor. The experiment was carried out on five groups of white laboratory mice, with group 1 (positive control) being healthy individuals; group 2 (negative control) - individuals infected with EPNT-5 cancer cells; group 3 (experiment) - infected individuals that received an injection of selenium nanoparticles; group 4 (experiment) - infected individuals that received an injection of selenium nanoparticles and immunoglobulin imG; group 5 (experiment) - infected individuals who received an injection of immunoglobulin imG. During the experiment, the development of the disease and the behavior of laboratory animals were monitored. After 4 weeks, blood was taken for a general and biochemical test, and the masses of the internal organs of laboratory mice were also examined.
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纳米硒抗肿瘤活性的研究
在科学文献中,关于硒纳米颗粒在药物开发中的可行性的研究被广泛提出。硒在治疗癌症、丙型肝炎、甲状腺疾病、心血管疾病、哮喘和其他疾病方面的积极作用已被研究。这篇科学论文介绍了硒纳米粒子对癌症肿瘤发展的影响的研究结果。实验采用5组实验小鼠,1组(阳性对照)为健康个体;2组(阴性对照)-感染EPNT-5癌细胞的个体;第三组(实验)——接受硒纳米颗粒注射的感染个体;第4组(实验)——接受硒纳米颗粒和免疫球蛋白imG注射的感染者;第5组(实验)——接受免疫球蛋白注射的感染者。在实验过程中,监测疾病的发展和实验动物的行为。4周后,取血进行常规和生化检查,并对实验小鼠的脏器肿块进行检查。
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