{"title":"Time for Molecular Glycobiology","authors":"Zhengliang L. Wu","doi":"10.4172/2168-958X.1000E106","DOIUrl":null,"url":null,"abstract":"Copyright: © 2012 Wu ZL. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Glycobiology, a field of research on glycans, is considered to be distinct from molecular biology, a field of research traditionally focused on protein and nucleic acids. The reason for this distinction is more due to methodological differences. The common practices for molecular biology including molecular cloning and detection methods are not available to glycobiology. However, with the recent technique advances, such as methods for glycosyltransferase assay, and availability of various new enzymatic tools, such as commercially active glycosyltransferases and sulfotransferases, research on glycobiology is going to be more similar to molecular biology and it is reasonable to say that glycobiology is going to enter into a new phase of molecular glycobiology.","PeriodicalId":92404,"journal":{"name":"Journal of glycobiology","volume":"2012 1","pages":"1-1"},"PeriodicalIF":0.0000,"publicationDate":"2012-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"4","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of glycobiology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4172/2168-958X.1000E106","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 4
分子糖生物学时间到了
版权所有:©2012吴志良。这是一篇根据知识共享署名许可协议发布的开放获取文章,该协议允许在任何媒体上不受限制地使用、分发和复制,前提是要注明原作者和来源。糖生物学是研究聚糖的一个领域,被认为与分子生物学不同,分子生物学传统上主要研究蛋白质和核酸。造成这种区别的原因更多是由于方法上的差异。分子生物学常用的方法,包括分子克隆和检测方法,在糖生物学中是不可用的。然而,随着近年来技术的进步,如糖基转移酶测定方法的出现,以及各种新的酶工具的出现,如具有商业活性的糖基转移酶和硫基转移酶,糖生物学的研究将更接近于分子生物学,可以说糖生物学将进入一个分子糖生物学的新阶段。
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