Role of PET-CT (Positron Emission Tomography-Computed Tomography) in Cancer Evaluation and Treatment

B. Vasundhara, P. Hemalatha, P.R.S.S.V. Raju
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Abstract

Context: Positron emission tomography is a nuclear medicine imaging that deals with physiological function using radioisotopes. With the most PET (Positron Emission Tomography) scanners in integration with the CT scanners of late, this technology has registered phenomenal growth. The small amount of radioactive material is called Radiotracers. Objective: Like 18 F-Fluro-deoxy-2-glucose has widely used. In this article, the author introduced clinical applications of PET out of 25 patients who studied hypermetabolic lesions in lymph nodes. Methods: PET imaging is coincidence imaging which is different from the other imaging technique PET image formed from multiple rings of detector crystals. Each decay positron travel in tissue annihila-tion reaction is going on. FDG is the most commonly used radiotracer to detect and stage various types of malignancies. Result: The field of PET/CT imaging cares for many oncology patients. PET improved localization of malignant lesions. It improved staging biopsy and therapy. Conclusion: Finally, studies to data showed 4% to 10% improvement in the overall accuracy of staging/restaging in lesions. If we use Monte Carlo simulation, OLINDA/EXM software may improve further with widely used.
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正电子发射断层扫描(PET-CT)在癌症评估和治疗中的作用
背景:正电子发射断层扫描是利用放射性同位素处理生理功能的核医学成像。随着最近大多数PET(正电子发射断层扫描)扫描仪与CT扫描仪的集成,这项技术已经取得了惊人的增长。少量的放射性物质被称为放射性示踪剂。目的:氟-脱氧-2-葡萄糖具有广泛的应用前景。在本文中,作者介绍了PET在25例淋巴结高代谢病变研究中的临床应用。方法:PET成像是不同于其他成像技术的重合成像,它是由探测器晶体的多个环形成的PET图像。每一次正电子衰变都在组织湮灭反应中进行。FDG是最常用的放射性示踪剂,用于检测和分期各种类型的恶性肿瘤。结果:PET/CT成像领域是许多肿瘤患者的关注领域。PET提高了恶性病变的定位。它改善了分期活检和治疗。结论:最后,研究数据显示,病变分期/再分期的总体准确性提高了4%至10%。如果采用蒙特卡罗模拟,OLINDA/EXM软件的广泛应用可能会进一步完善。
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