Does sodium bicarbonate based extra-cellular buffering support reduce high intensity exercise-induced fatigue and enhance short-term recovery assessed by selected blood biochemical indices?

IF 4.2 2区 医学 Q1 SPORT SCIENCES Biology of Sport Pub Date : 2024-01-01 Epub Date: 2023-05-25 DOI:10.5114/biolsport.2024.125591
Krzysztof Durkalec-Michalski, Joanna Kamińska, Bryan Saunders, Andrzej Pokrywka, Igor Łoniewski, Michal Steffl, Tomasz Podgórski
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Abstract

Exercise-induced metabolic processes induce muscle acidification which contributes to a reduction in the ability to perform repeated efforts. Alkalizing agents such as sodium bicarbonate (NaHCO3) prevent large blood pH changes, however, there is no evidence on whether regulation of acid-base balance may also support whole body homeostasis monitored through heamatological and biochemical blood markers in a dose-dependent manner. Thirty Cross-Fit-trained participants were studied in a randomized, multi cross-over, placebo (PLA)-controlled double-blind manner in which they performed a control session (CTRL, without supplementation), three NaHCO3 visits (three different doses) and PLA (sodium chloride in an equimolar amount of sodium as NaHCO3). Each visit consisted of two 30-s Wingate tests separated by CrossFit-specific benchmarks (Wall Balls and Burpees - both performed for 3 min). Blood samples were collected at rest, immediately post-exercise and after 45 min recovery. Significant differences between visits appeared for blood pH, percentage of lymphocytes and granulocytes, red blood cells count and haemoglobin concentration at post-exercise and 45-min recovery, and for white blood cells count, percentage of monocytes, concentration of magnesium and creatinine at 45-min recovery. Most of the observed differences for heamatological and biochemical markers were significant compared to CTRL, but not different after PLA. NaHCO3 supplementation compared to PLA did not significantly affect exercise or recovery shifts in studied blood indicators. However, the changes in these markers after NaHCO3 and PLA in relation to CTRL indicate a possible role of sodium.

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以碳酸氢钠为基础的细胞外缓冲支持能否减轻高强度运动引起的疲劳,并通过选定的血液生化指标评估增强短期恢复?
运动引起的新陈代谢过程会导致肌肉酸化,从而降低重复运动的能力。碳酸氢钠(NaHCO3)等碱性制剂可防止血液 pH 值发生较大变化,但没有证据表明酸碱平衡的调节是否也能以剂量依赖的方式支持通过血液血液学和生化指标监测的全身平衡。我们对 30 名接受过 Cross-Fit 训练的参与者进行了随机、多交叉、安慰剂(PLA)对照双盲研究,其中他们分别进行了一次对照训练(CTRL,无补充剂)、三次 NaHCO3 访问(三种不同剂量)和 PLA(氯化钠与 NaHCO3 的钠等摩尔量)。每次检查包括两次 30 秒的 Wingate 测试,中间以 CrossFit 特定基准(壁球和 Burpees - 均为 3 分钟)隔开。在休息、运动后立即和恢复 45 分钟后采集血液样本。在运动后和 45 分钟恢复期,血液 pH 值、淋巴细胞和粒细胞百分比、红细胞计数和血红蛋白浓度,以及在 45 分钟恢复期,白细胞计数、单核细胞百分比、镁浓度和肌酐在各访问之间存在显著差异。观察到的大多数血液学和生化指标与 CTRL 相比差异显著,但与 PLA 相比差异不大。与 PLA 相比,补充 NaHCO3 对所研究的血液指标的运动或恢复变化没有明显影响。不过,与 CTRL 相比,补充 NaHCO3 和 PLA 后这些指标的变化表明钠可能起了作用。
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来源期刊
Biology of Sport
Biology of Sport 生物-运动科学
CiteScore
8.20
自引率
12.50%
发文量
113
审稿时长
>12 weeks
期刊介绍: Biology of Sport is the official journal of the Institute of Sport in Warsaw, Poland, published since 1984. Biology of Sport is an international scientific peer-reviewed journal, published quarterly in both paper and electronic format. The journal publishes articles concerning basic and applied sciences in sport: sports and exercise physiology, sports immunology and medicine, sports genetics, training and testing, pharmacology, as well as in other biological aspects related to sport. Priority is given to inter-disciplinary papers.
期刊最新文献
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