Tailored biomedical materials for wound healing.

IF 6.3 1区 医学 Q1 DERMATOLOGY Burns & Trauma Pub Date : 2023-10-26 eCollection Date: 2023-01-01 DOI:10.1093/burnst/tkad040
Wenhui Liu, Lihua Zu, Shanzheng Wang, Jingyao Li, Xiaoyuan Fei, Meng Geng, Chunlei Zhu, Hui Shi
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Abstract

Wound healing is a long-term, multi-stage biological process that mainly includes haemostatic, inflammatory, proliferative and tissue remodelling phases. Controlling infection and inflammation and promoting tissue regeneration can contribute well to wound healing. Smart biomaterials offer significant advantages in wound healing because of their ability to control wound healing in time and space. Understanding how biomaterials are designed for different stages of wound healing will facilitate future personalized material tailoring for different wounds, making them beneficial for wound therapy. This review summarizes the design approaches of biomaterials in the field of anti-inflammatory, antimicrobial and tissue regeneration, highlights the advanced precise control achieved by biomaterials in different stages of wound healing and outlines the clinical and practical applications of biomaterials in wound healing.

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为伤口愈合量身定制的生物医学材料。
伤口愈合是一个长期、多阶段的生物学过程,主要包括止血、炎症、增殖和组织重塑阶段。控制感染和炎症以及促进组织再生可以很好地促进伤口愈合。智能生物材料在伤口愈合方面具有显著优势,因为它们能够在时间和空间上控制伤口愈合。了解生物材料是如何为伤口愈合的不同阶段设计的,将有助于未来为不同伤口定制个性化材料,使其对伤口治疗有益。本文综述了生物材料在抗炎、抗菌和组织再生领域的设计方法,重点介绍了生物材料对伤口愈合不同阶段实现的先进精确控制,并概述了生物材料的临床和实际应用。
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来源期刊
Burns & Trauma
Burns & Trauma 医学-皮肤病学
CiteScore
8.40
自引率
9.40%
发文量
186
审稿时长
6 weeks
期刊介绍: The first open access journal in the field of burns and trauma injury in the Asia-Pacific region, Burns & Trauma publishes the latest developments in basic, clinical and translational research in the field. With a special focus on prevention, clinical treatment and basic research, the journal welcomes submissions in various aspects of biomaterials, tissue engineering, stem cells, critical care, immunobiology, skin transplantation, and the prevention and regeneration of burns and trauma injuries. With an expert Editorial Board and a team of dedicated scientific editors, the journal enjoys a large readership and is supported by Southwest Hospital, which covers authors'' article processing charges.
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