Adult neurogenesis research in China

IF 1.7 4区 生物学 Q4 CELL BIOLOGY Development Growth & Differentiation Pub Date : 2023-10-29 DOI:10.1111/dgd.12900
Xing Luo, Mingyue Xu, Weixiang Guo
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Abstract

Neural stem cells are multipotent stem cells that generate functional newborn neurons through a process called neurogenesis. Neurogenesis in the adult brain is tightly regulated and plays a pivotal role in the maintenance of brain function. Disruption of adult neurogenesis impairs cognitive function and is correlated with numerous neurologic disorders. Deciphering the mechanisms underlying adult neurogenesis not only advances our understanding of how the brain functions, but also offers new insight into neurologic diseases and potentially contributes to the development of effective treatments. The field of adult neurogenesis is experiencing significant growth in China. Chinese researchers have demonstrated a multitude of factors governing adult neurogenesis and revealed the underlying mechanisms of and correlations between adult neurogenesis and neurologic disorders. Here, we provide an overview of recent advancements in the field of adult neurogenesis due to Chinese scientists.

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中国成人神经发生研究。
神经干细胞(NSCs)是一种多能干细胞,通过一个称为神经发生的过程产生功能性新生神经元。成人大脑的神经发生受到严格调控,在维持大脑功能方面发挥着关键作用。成人神经发生中断会损害认知功能,并与许多神经系统疾病有关。解读成人神经发生的机制不仅促进了我们对大脑功能的理解,还为神经疾病提供了新的见解,并可能有助于开发有效的治疗方法。成人神经发生领域在中国正经历着显著的发展。中国研究人员已经证明了控制成人神经发生的多种因素,并揭示了成人神经发生与神经系统疾病之间的相关性和潜在机制。在这里,我们概述了中国科学家在成人神经发生领域的最新进展。这篇文章受版权保护。保留所有权利。
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来源期刊
Development Growth & Differentiation
Development Growth & Differentiation 生物-发育生物学
CiteScore
4.60
自引率
4.00%
发文量
62
审稿时长
6 months
期刊介绍: Development Growth & Differentiation (DGD) publishes three types of articles: original, resource, and review papers. Original papers are on any subjects having a context in development, growth, and differentiation processes in animals, plants, and microorganisms, dealing with molecular, genetic, cellular and organismal phenomena including metamorphosis and regeneration, while using experimental, theoretical, and bioinformatic approaches. Papers on other related fields are also welcome, such as stem cell biology, genomics, neuroscience, Evodevo, Ecodevo, and medical science as well as related methodology (new or revised techniques) and bioresources. Resource papers describe a dataset, such as whole genome sequences and expressed sequence tags (ESTs), with some biological insights, which should be valuable for studying the subjects as mentioned above. Submission of review papers is also encouraged, especially those providing a new scope based on the authors’ own study, or a summarization of their study series.
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