Fluoride exposure and prevalence of osteochondroma in drinking water Endemic fluorosis areas of Heilongjiang Province, China: a cross-sectional study.

IF 2.2 4区医学 Q3 ENVIRONMENTAL SCIENCES International Journal of Environmental Health Research Pub Date : 2024-08-01 Epub Date: 2023-11-03 DOI:10.1080/09603123.2023.2277336

Yongzheng Ma, Yang Liu, Xiaona Liu, Mang Li, Jing Cui, Zhizhong Guan, Junrui Pei, Yanhui Gao

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Abstract

To investigate the relationship between fluoride exposure and Osteochondroma (OC) prevalence, a cross-sectional study was conducted in drinking water endemic fluorosis areas of Heilongjiang Province, China. Our study first reported that the prevalence of OC was 2.3% in drinking water endemic fluorosis areas of Heilongjiang Province, China, and no difference in gender. Logistic regression analysis found that compared to 1^st quartile participants, the prevalence of OC was 73% lower in the 2^nd quartile participants of WF (Water fluoride), and 3.4 times higher among the 2^nd quartile UF (Urinary fluoride) participants. Our study suggests that 0.259-0.420 mg/L of WF may be considered an appropriate level for reducing OC prevalence, while UF (≥0.750 mg/L) could slightly increase the prevalence of OC. In summary, the link between fluoride and OC prevalence is complicated and needs to be further investigated in a cohort population.

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饮用水氟中毒地区氟暴露与骨软骨瘤患病率：一项横断面研究。

为探讨氟暴露与骨软骨瘤（OC）患病率的关系，对黑龙江省饮水型氟中毒病区进行了横断面研究。本研究首次报道黑龙江省饮水型氟中毒病区OC患病率为2.3%，且无性别差异。Logistic回归分析发现，与第一个四分位数的参与者相比，WF（氟化水）第二四分位数参与者的OC患病率低73%，UF（尿氟）第二四分位数参与者高3.4倍。我们的研究表明0.259-0.420 mg/L的WF可被认为是降低OC患病率的合适水平，而UF（≥0.750 mg/L）可略微增加OC的患病率。总之，氟化物和OC患病率之间的联系很复杂，需要在队列人群中进一步研究。

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来源期刊

International Journal of Environmental Health Research 医学-公共卫生、环境卫生与职业卫生

CiteScore

6.70

自引率

3.10%

发文量

134

审稿时长

>12 weeks

期刊介绍： International Journal of Environmental Health Research ( IJEHR ) is devoted to the rapid publication of research in environmental health, acting as a link between the diverse research communities and practitioners in environmental health. Published articles encompass original research papers, technical notes and review articles. IJEHR publishes articles on all aspects of the interaction between the environment and human health. This interaction can broadly be divided into three areas: the natural environment and health – health implications and monitoring of air, water and soil pollutants and pollution and health improvements and air, water and soil quality standards; the built environment and health – occupational health and safety, exposure limits, monitoring and control of pollutants in the workplace, and standards of health; and communicable diseases – disease spread, control and prevention, food hygiene and control, and health aspects of rodents and insects. IJEHR is published in association with the International Federation of Environmental Health and includes news from the Federation of international meetings, courses and environmental health issues.