Hydrazide Schiff base Compound Containing Triphenylphosphonium Units for Fluorescence Sensing of Al3+ and its real Sample Applications.

Abstract

Al³⁺ excess in the body can cause many diseases. The development of chemosensors for the detection of Al³⁺ is therefore highly desirable. A hydrazide Schiff base compound containing triphenylphosphonium units (ER) was prepared and used as fluorescence turn-on sensor for the sensing of Al³⁺. Detection of Al³⁺ among various metals has been achieved successfully through the formation of Al³⁺-ligand coordination complexes. To detect Al³⁺, the "turn on" property of the fluorogenic chemosensor was investigated. Fluorescence sensing studies were carried out in CH₃OH-Water (v/v, 9/1, pH 7.0) at λ_em = 528 nm. The LOD for sensing of Al³⁺ was found to be 0.129 µM. Using Job's graph, the stoichiometric ratio of ER- Al³⁺ was determined to be 1:1. The binding constant was determined to be 1.7 × 10⁷ M^-1 between Al3 + and the chemosensor ER. Finally, the determination of Al³⁺ in real herbal teas was carried out by using the sensing function of the chemosensor ER.