Predicting perineal trauma during childbirth using data from a general obstetric population.

HRB open research Pub Date : 2023-10-10 eCollection Date: 2022-01-01 DOI:10.12688/hrbopenres.13656.2
Gillian M Maher, Laura J O'Byrne, Joye McKernan, Paul Corcoran, Richard A Greene, Ali S Khashan, Fergus P McCarthy
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Abstract

Background: Perineal trauma is a common complication of childbirth and can have serious impacts on long-term health. Few studies have examined the combined effect of multiple risk factors. We developed and internally validated a risk prediction model to predict third and fourth degree perineal tears using data from a general obstetric population.

Methods: Risk prediction model using data from all singleton vaginal deliveries at Cork University Maternity Hospital (CUMH), Ireland during 2019 and 2020. Third/fourth degree tears were diagnosed by an obstetrician or midwife at time of birth and defined as tears that extended into the anal sphincter complex or involved both the anal sphincter complex and anorectal mucosa. We used univariable and multivariable logistic regression with backward stepwise selection to develop the models. Candidate predictors included infant sex, maternal age, maternal body mass index, parity, mode of delivery, birthweight, post-term delivery, induction of labour and public/private antenatal care. We used the receiver operating characteristic (ROC) curve C-statistic to assess discrimination, and bootstrapping techniques were used to assess internal validation.

Results: Of 8,403 singleton vaginal deliveries, 8,367 (99.54%) had complete data on predictors for model development. A total of 128 women (1.53%) had a third/fourth degree tear. Three variables remained in the final model: nulliparity, mode of delivery (specifically forceps delivery or ventouse delivery) and increasing birthweight (per 100 gram increase) (C-statistic: 0.75, 95% CI: 0.71, 0.79). We developed a nomogram to calculate individualised risk of third/fourth degree tears using these predictors. Bootstrapping indicated good internal performance.

Conclusions: Use of our nomogram can provide an individualised risk assessment of third/fourth degree tears and potentially aid counselling of women on their potential risk.

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使用来自一般产科人群的数据预测分娩期间的会阴创伤。
背景:会阴创伤是一种常见的分娩并发症,会对长期健康产生严重影响。很少有研究考察多种风险因素的综合作用。我们开发并内部验证了一个风险预测模型,利用普通产科人群的数据预测三度和四度会阴撕裂。方法:使用2019年和2020年爱尔兰科克大学妇产医院(CUMH)所有单胎阴道分娩数据的风险预测模型。产科医生或助产士在出生时诊断出三度/四度撕裂,并将其定义为延伸到肛门括约肌复合体或涉及肛门括约肌复合体和肛门直肠粘膜的撕裂。我们使用单变量和多变量逻辑回归和后向逐步选择来开发模型。候选预测因素包括婴儿性别、母亲年龄、母亲体重指数、产次、分娩方式、出生体重、足月分娩、引产和公共/私人产前护理。我们使用受试者工作特性(ROC)曲线C统计量来评估区分,并使用自举技术来评估内部验证。结果:在8403例单例阴道分娩中,8367例(99.54%)有完整的模型开发预测数据。共有128名妇女(1.53%)患有三/四度撕裂。最终模型中保留了三个变量:未产妇、分娩方式(特别是产钳分娩或腹式分娩)和出生体重增加(每增加100克)(C统计量:0.75,95%置信区间:0.71,0.79)。我们使用这些预测因子开发了一个列线图来计算三度/四度撕裂的个体风险。引导表明内部性能良好。结论:使用我们的列线图可以对三度/四度眼泪进行个性化的风险评估,并有助于对女性的潜在风险进行咨询。
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6 weeks
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