Comments and illustrations of the WFUMB CEUS liver guidelines: Cystic fibrosis associated liver disease.

Medical ultrasonography Pub Date : 2024-09-16 Epub Date: 2023-10-26 DOI:10.11152/mu-4297
Kathleen Möller, Thomas Friedrich, Ehsan Safai Zadeh, Christian Görg, Christian Jenssen, Michael Hocke, Chiara De Molo, Carla Serra, Yi Dong, Xin Wu Cui, Adrian Lim, Klaus Dirks, David Srivastava, Christoph F Dietrich
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Abstract

In this series of articles with comments and illustrations on the World Federation for Medicine and Biology (WFUMB) guidelines on contrast-enhanced ultrasound (CEUS) the topics of very rare focal liver lesions (FLL) are discussed. Improving the detection and characterization of the most common FLL are the main topics of these guidelines. The focus of this review is on the many manifestations of cystic fibrosis-related liver disease (CFLD). These include focal biliary fibrosis, liver cirrhosis, vascular manifestations with nodular regenerative hyperplasia and portal hypertension with or without cirrhosis. This article describes the diverse changes of liver involvement in cystic fibrosis and their appearance on ultrasound, duplex sonography, and contrast enhanced ultrasonography. This knowledge and the imaging should help to recognize liver manifestations in time and enable a correct interpretation of ultrasound images in CF in the corresponding clinical situation.

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WFUMB CEUS肝脏指南的注释和插图:囊性纤维化相关肝病。
在这一系列对世界医学与生物学联合会(WFUMB)超声造影(CEUS)指南的评论和插图文章中,讨论了非常罕见的局灶性肝损伤(FLL)的主题。改进最常见FLL的检测和表征是这些指南的主要主题。这篇综述的重点是囊性纤维化相关肝病(CFLD)的许多表现。其中包括局灶性胆汁纤维化、肝硬化、伴有结节性再生性增生的血管表现以及伴有或不伴有肝硬化的门静脉高压。本文描述了囊性纤维化肝脏受累的各种变化及其在超声、双相超声和增强超声上的表现。这些知识和成像应有助于及时识别肝脏表现,并在相应的临床情况下正确解释CF中的超声图像。
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