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Diagnostic accuracy of transcranial ultrasonography for detecting stenosis in patients with acute ischaemic stroke: a systematic review and meta-analysis. 经颅超声波检测急性缺血性脑卒中患者血管狭窄的诊断准确性:系统综述和荟萃分析。
Pub Date : 2024-10-21 DOI: 10.11152/mu-4413
Xiaofei Zhu, Yan Li, Wei Xia, Wenfu Wang

Aim: Transcranial ultrasonography, including transcranial doppler (TCD) and transcranial colour-coded duplex/sonography (TCCD/TCCS), offers potential benefits in the evaluation of cerebrovascular patency, but its accuracy remains under scrutiny. Hence, this study aims to investigate the diagnostic accuracy of transcranial ultrasonography for detecting stenosis in acute ischaemic stroke patients.

Material and methods: We systematically reviewed the databases such as CINAHL, SCOPUS, EMBASE, MEDLINE, Cochrane Library, Google Scholar, and ScienceDirect from inception till June 2023. Studies were eligible if they compared the diagnostic role of transcranial ultrasonography with established techniques, and reported accuracy parameters such as sensitivity, specificity, positive and negative likelihood ratios. Subgroup analysis was performed for TCD and TCCD/TCCS.

Results: Seventeen studies involving 1496 participants were included. The pooled sensitivity and specificity of transcranial ultrasonography were 90% and 95% respectively. For TCD, the sensitivity and specificity were 87% and 93% respectively. TCCD/TCCS showed sensitivity 98% and specificity 97%. High clinical value was evident in both TCD and TCCD/TCCS, with heterogeneity across studies but no observable publication bias.

Conclusion: Transcranial ultrasonography, including both TCD and TCCD/TCCS, demonstrates high diagnostic accuracy in detecting stenosis in patients with acute ischaemic stroke. These findings support the utility of these methods as reliable, non-invasive tools for cerebrovascular assessment.

目的:经颅超声造影,包括经颅多普勒(TCD)和经颅彩色编码双相/超声造影(TCCD/TCCS),在评估脑血管通畅性方面具有潜在优势,但其准确性仍有待进一步研究。因此,本研究旨在探讨经颅超声检查在急性缺血性卒中患者中检测血管狭窄的诊断准确性:我们系统地查阅了从开始到 2023 年 6 月的 CINAHL、SCOPUS、EMBASE、MEDLINE、Cochrane Library、Google Scholar 和 ScienceDirect 等数据库。如果研究比较了经颅超声造影与既有技术的诊断作用,并报告了敏感性、特异性、阳性和阴性似然比等准确性参数,则符合条件。对 TCD 和 TCCD/TCCS 进行了分组分析:结果:共纳入 17 项研究,涉及 1496 名参与者。经颅超声造影的汇总灵敏度和特异度分别为 90% 和 95%。TCD 的敏感性和特异性分别为 87% 和 93%。TCCD/TCCS 的敏感性为 98%,特异性为 97%。TCD和TCCD/TCCS都具有很高的临床价值,不同研究之间存在异质性,但没有明显的发表偏倚:结论:经颅超声检查(包括 TCD 和 TCCD/TCCS)在检测急性缺血性卒中患者血管狭窄方面具有很高的诊断准确性。这些研究结果支持这些方法作为可靠、无创的脑血管评估工具的实用性。
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引用次数: 0
The impact of bowel preparation on MRI scans for confirming rectosigmoid endometriosis detected by transvaginal ultrasonography. 经阴道超声波检查确认直肠乙状结肠子宫内膜异位症时,肠道准备工作对核磁共振扫描的影响。
Pub Date : 2024-10-21 DOI: 10.11152/mu-4441
Cemil Gürses, Alpaslan Yavuz, Nevfel Kahvecioğlu, Mustafa Yalçın, Gizem Ünal, Burak Karadağ, Hüseyin Çiyiltepe

Aims: The study aims to assess the impact of bowel preparation on MRI scans in diagnosing rectosigmoid endometriosis (RSE) and to examine the level of agreement among investigators, including radiologists and clinicians with varying levels of MRI experience.

Material and methods: Fifty-eight patients underwent MRI scans, with 34 showing RSE and 24 without involvement, according to TVUS as the reference standard. The scans were conducted both with and without a bowel preparatory protocol (BPP).

Results: The highest concordance was observed in the group 4, which included patients with RSE and BPP, with a Kappa value of 0.47-0.52. In contrast, for groups with MRI scans without the BPP, there was no consistency among the investigators (Kappa <0.20). The sensitivity, specificity, positive predictive value, and negative predictive value were 0.72, 0.47, 0.72, and 0.47 without BPP, and increased to 0.82, 0.74, 0.85, and 0.74, respectively, after BPP.

Conclusions: The results reveal that the concordance between investigators in detecting RSE via MRI scan improves with the use of BPP. Additionally, the success rate of MRI and TVUS for detecting RSE can be comparable, but only if bowel preparatory techniques are utilized during MRI scans.

目的:该研究旨在评估肠道准备对核磁共振扫描诊断直肠乙状结肠子宫内膜异位症(RSE)的影响,并检查研究人员(包括具有不同核磁共振经验的放射科医生和临床医生)之间的一致程度:58例患者接受了核磁共振扫描,其中34例显示RSE,24例未受累,以TVUS为参考标准。扫描同时进行和不进行肠道准备方案(BPP):结果:第 4 组(包括 RSE 和 BPP 患者)的一致性最高,Kappa 值为 0.47-0.52。相比之下,在没有 BPP 的 MRI 扫描组中,研究人员之间没有一致性(Kappa 结论):结果表明,使用 BPP 后,研究人员之间通过 MRI 扫描检测 RSE 的一致性提高了。此外,磁共振成像和 TVUS 检测 RSE 的成功率不相上下,但前提是在磁共振成像扫描时使用肠道准备技术。
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引用次数: 0
Pancreatic cancer liver metastasis mimicking focal nodular hyperplasia. A case report. 模仿局灶性结节增生的胰腺癌肝转移。病例报告。
Pub Date : 2024-10-21 DOI: 10.11152/mu-4442
Oliver Wedel Fischer, Tobias Freyberg Justesen, Christian Pallson Nolsøe, Christo Pentchev Pentchev, Evelina Georgieva Atanasova

Metastases to the liver from gastroenteropancreatic neuroendocrine tumors are varied in their presentation and echogenicity on ultrasound. We present a case of adenocarcinoma of the pancreas with sporadic neuroendocrine differentiation and metastasis to the liver, referred for inclusion in a clinical study. Standard ultrasound showed two hypoechoic focal liver lesions. On contrast enhanced ultrasound (CEUS) the larger tumour bore an enhancement resemblance to that of a focal nodular hyperplasia (FNH). This result necessitated a histological confirmation, which indicated neuroendocrine, highly differentiated tumour tissue, compatible with metastasis from the patient's pancreatic cancer. This case showcases the role of histologically confirmed diagnosis in liver lesions with atypical imaging characteristics, especially in patients with a history of malignancy and potential oncological treatment.

胃肠胰神经内分泌肿瘤转移到肝脏的表现和超声回声各不相同。我们介绍了一例胰腺腺癌伴有散发性神经内分泌分化并转移至肝脏的病例,该病例被转介到临床研究中。标准超声显示肝脏有两个低回声病灶。对比增强超声(CEUS)显示,较大的肿瘤增强后与局灶性结节增生(FNH)相似。这一结果需要进行组织学确认,结果显示为神经内分泌、高分化肿瘤组织,与患者的胰腺癌转移相符。该病例展示了组织学确诊在具有非典型影像学特征的肝脏病变中的作用,尤其是在有恶性肿瘤病史和可能接受肿瘤治疗的患者中。
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引用次数: 0
Advancements and challenges in Shear-Wave Elastography of tendons: a comprehensive review. 肌腱剪切波弹性成像技术的进步与挑战:全面回顾。
Pub Date : 2024-10-17 DOI: 10.11152/mu-4444
Michael-Andrei Pelea, Oana Șerban, Maria Bădărînză, Daniela Fodor

Shear-Wave Elastography (SWE) has emerged as a promising non-invasive imaging technique for assessing the mechanical properties of tendons, particularly larger and more superficially located tendons of the body. Despite its potential, significant variability in SWE measurements exists due to differences in protocols, positioning, and equipment. Standardizing these factors, enhancing operator training, and reporting reliability metrics are crucial to improve the consistency and comparability of SWE data. This review aims to synthesize current knowledge and report on the existing practices in tendon SWE. By addressing the current challenges and variability, SWE has the potential to become a reliable tool for diagnosing and monitoring tendon pathologies, ultimately enhancing patient care and outcomes.

剪切波弹性成像(SWE)已成为评估肌腱(尤其是人体较大且位置较浅的肌腱)机械特性的一种很有前途的无创成像技术。尽管 SWE 很有潜力,但由于操作规程、定位和设备的不同,其测量结果存在很大差异。要提高 SWE 数据的一致性和可比性,将这些因素标准化、加强操作员培训和报告可靠性指标至关重要。本综述旨在综合现有知识,报告肌腱 SWE 方面的现有实践。通过应对当前的挑战和变异性,SWE 有可能成为诊断和监测肌腱病变的可靠工具,最终提高患者护理和治疗效果。
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引用次数: 0
Ultrasound for breast cancer detection: A bibliometric analysis of global trends between 2004 and 2024. 超声波乳腺癌检测:对 2004 年至 2024 年全球趋势的文献计量分析。
Pub Date : 2024-10-17 DOI: 10.11152/mu-4443
Ya-Yu Sun, Xiao-Tong Shi, Li-Long Xu

With the advancement of computer technology and imaging equipment, ultrasound has emerged as a crucial tool in breast cancer diagnosis. To gain deeper insights into the research landscape of ultrasound in breast cancer diagnosis, this study employed bibliometric methods for a comprehensive analysis spanning from 2004 to 2024, analyzing 3523 articles from 2176 institutions in 82 countries/regions. Over this period, publications on ultrasound diagnosis of breast cancer showed a fluctuating growth trend from 2004 to 2024. Notably, China, Seoul National University and Kim EK emerged as leading contributors in ultrasound for breast cancer detection, with the most published and cited journals being Ultrasound Med Biol and Radiology. The research spots in this area included "breast lesion", "dense breast" and "breast-conserving surgery", while "machine learning", "ultrasonic imaging", "convolutional neural network", "case report", "pathological complete response", "deep learning", "artificial intelligence" and "classification" are anticipated to become future research frontiers. This groundbreaking bibliometric analysis and visualization of ultrasonic breast cancer diagnosis publications offer clinical medical professionals a reliable research focus and direction.

随着计算机技术和成像设备的发展,超声波已成为乳腺癌诊断的重要工具。为了更深入地了解超声诊断乳腺癌的研究现状,本研究采用文献计量学方法进行了全面分析,分析时间跨度从 2004 年到 2024 年,分析了来自 82 个国家/地区 2176 个机构的 3523 篇文章。在此期间,从 2004 年到 2024 年,有关乳腺癌超声诊断的论文呈波动增长趋势。值得注意的是,中国、首尔国立大学和 Kim EK 成为乳腺癌超声检测领域的主要贡献者,发表和引用最多的期刊是《超声医学生物学》和《放射学》。该领域的研究热点包括 "乳腺病变"、"致密乳腺 "和 "保乳手术",而 "机器学习"、"超声成像"、"卷积神经网络"、"病例报告"、"病理完全反应"、"深度学习"、"人工智能 "和 "分类 "预计将成为未来的研究前沿。这种开创性的超声乳腺癌诊断出版物文献计量分析和可视化为临床医学专业人员提供了可靠的研究重点和方向。
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引用次数: 0
An [illustrative] update on pediatric emergency ultrasound: part 3 - cerebral, musculoskeletal and other applications. 儿科急诊超声波的[说明性]更新:第三部分--大脑、肌肉骨骼及其他应用。
Pub Date : 2024-10-17 DOI: 10.11152/mu-4440
Simone Schwarz, Yi Dong, Peter J Snelling, Beatrice Hoffmann, Nasenien Nourkami-Tutdibi, Yun-Lin Huang, Sheng Chen, Andrius Cekuolis, Rasa Augustiniene, Dagmar Schreiber-Dietrich, Lara Grevelding, Christoph F Dietrich

Point-of-care ultrasound (POCUS) plays an essential role in pediatric emergency medicine by improving diagnostics and procedural safety. The role of POCUS in the care of pediatric patients in the emergency department has expanded considerably in recent years. Cranial and musculoskeletal imaging has significant potential, yet POCUS has also become a vital tool for common procedures, such as central and difficult peripheral intravenous access. The purpose of this article is to provide an overview of pediatric POCUS applications for cranial, small parts (head, eyes, nose, throat, and soft tissue), musculoskeletal, and common procedural applications, forming the third part of the series.

护理点超声(POCUS)可提高诊断和手术安全性,在儿科急诊医学中发挥着至关重要的作用。近年来,POCUS 在急诊科儿科病人护理中的作用已大大扩展。颅骨和肌肉骨骼成像具有巨大潜力,但 POCUS 也已成为中心静脉和困难外周静脉通路等常见手术的重要工具。本文旨在概述儿科 POCUS 在颅脑、小部位(头、眼、鼻、喉和软组织)、肌肉骨骼和常见手术中的应用,是本系列文章的第三部分。
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引用次数: 0
A longitudinal 5-year study for the prediction of HCC, death and liver decompensation by ARFI elastography. 通过 ARFI 弹性成像预测肝癌、死亡和肝脏失代偿的 5 年纵向研究。
Pub Date : 2024-09-30 DOI: 10.11152/mu-4438
Lukas Pfeifer, Moritz Klueppel, Werner Adler, Barbara Schellhaas, Markus Neurath, Deike Strobel

Aim: Numerous studies have evaluated elastography for the staging of liver fibrosis. Fewer studies were performed investigating the prognostic relevance using transient elastography (TE), although with promising results. This study was designed to evaluate the prognostic relevance of ARFI elastography.

Material and method: Patients receiving ARFI elastography in our ultrasound department between 2010 and 2012 were initially screened for an ARFI examination with a clinical follow-up of at least 5 years. The following events were recorded: liver related death, liver unrelated death, HCC, liver decompensation/ variceal bleeding.

Results: A total of 335 patients were included in the final analysis with an ARFI examination of the liver and a follow-up of 60 months. Within the observation interval the number of events with corresponding AUROCs (shown with 95% confidence interval) were: overall death (n=49, 0.76 [0.69 - 0.83]), liver related death (n=25, 0.85 [0.77 - 0.93]), liver unrelated death (n=24, 0.66 [0.55 - 0.77]), HCC (n=15, 0.80 [0.72 - 0.87]), liver related complications/variceal bleeding (n=34, 0.87 [0.82 - 0.93]). In the group of patients with ARFI values suggestive of cirrhosis (equal to or above 1.80 m/s; n=110) higher values (<2.5 m/s vs. >= 2.5 m/s) where associated with a significant decline in liver related survival (p=0.007).

Conclusion: ARFI elastography seems to have a good diagnostic accuracy for the prediction of liver related death and decompensation. Further it seems to allow a risk stratification in patients with cirrhosis suspicious elastography values.

目的:许多研究对肝纤维化分期的弹性成像进行了评估。使用瞬时弹性成像(TE)对预后相关性进行调查的研究较少,尽管结果令人鼓舞。本研究旨在评估ARFI弹性成像的预后相关性:对 2010 年至 2012 年期间在本院超声科接受 ARFI 弹性成像检查的患者进行初步筛查,并进行至少 5 年的临床随访。记录以下事件:与肝脏相关的死亡、与肝脏无关的死亡、HCC、肝功能失代偿/静脉曲张出血:共有 335 名患者接受了肝脏 ARFI 检查,随访时间为 60 个月。在观察区间内,事件数量及相应的 AUROCs(显示 95% 置信区间)分别为:总体死亡(49 人,0.76 [0.69 - 0.83])、肝脏相关死亡(25 人,0.85 [0.77 - 0.93])、肝脏无关死亡(n=24,0.66 [0.55 - 0.77])、HCC(n=15,0.80 [0.72 - 0.87])、肝脏相关并发症/静脉出血(n=34,0.87 [0.82 - 0.93])。在ARFI值提示肝硬化(等于或高于1.80 m/s;n=110)的患者组中,更高值(=2.5 m/s)与肝脏相关存活率显著下降有关(p=0.007):结论:ARFI弹性成像在预测与肝脏相关的死亡和失代偿方面具有良好的诊断准确性。此外,它似乎还能对肝硬化可疑弹性成像值患者进行风险分层。
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引用次数: 0
Endoscopy and endoscopic ultrasound for embedded or migratory digestive foreign body. 通过内窥镜和内窥镜超声波检查嵌入或移位的消化道异物。
Pub Date : 2024-09-30 DOI: 10.11152/mu-4437
Jia Xie, Yan Qin, Mojin Wang, Rui Wang

Embedded or migratory ingested foreign bodies (FBs) may be a disaster when not found intraluminally and can be seriously life-threatening. Endoscopic ultrasound (EUS) has advantages of transmural, close range and real-time imaging. Under its guidance, minimally invasive endoscopic removal of FBs and abscess drainage become available and safe to avoid unnecessary surgery. However, relatively few diagnostic applications of EUS have been reported. Endoscopic removal and abscess drainage with or without EUS-guidance were even scarce. We found 21 cases of migratory FBs reported in which EUS was used to diagnose and/or treat including our case. We further summarized clinical characteristics and EUS manifestations of embedded or migratory FBs for future differentiation, and treatment strategies by endoscopy and EUS. EUS is a valuable tool in recognizing and differentiating embedded or migratory FBs. EUS-guided endoscopic removal is a minimally invasive, safe and innovative solution. EUS with novel device also assists in sufficient and secure drainage for FBs related abscess collections. A multidisciplinary team consult is sometimes mandatory for complicated cases. This would break a conceptual barrier in therapeutic endoscopy.

嵌顿或移位的食入异物(FBs)如果不能在腔内发现,可能会酿成大祸,严重时会危及生命。内窥镜超声(EUS)具有经膜、近距离和实时成像的优势。在其引导下,内窥镜微创切除 FB 和脓肿引流变得可行且安全,从而避免了不必要的手术。然而,有关 EUS 诊断应用的报道相对较少。在 EUS 引导下或不在 EUS 引导下进行内窥镜切除和脓肿引流的病例更是少之又少。我们发现,包括本病例在内,有 21 例移行性 FB 病例报道使用 EUS 进行诊断和/或治疗。我们进一步总结了埋藏性或移行性 FB 的临床特征和 EUS 表现,以便将来进行鉴别,并总结了内镜和 EUS 的治疗策略。EUS 是识别和区分嵌顿性或移行性 FB 的重要工具。EUS 引导下的内窥镜切除术是一种微创、安全和创新的解决方案。使用新型装置的 EUS 还有助于充分、安全地引流与 FB 相关的脓肿。对于复杂病例,有时必须进行多学科团队会诊。这将打破治疗性内窥镜的概念障碍。
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引用次数: 0
How to perform Point of Care Ultrasound at resuscitation and when it is useful. 如何在复苏时进行护理点超声检查以及何时使用。
Pub Date : 2024-09-30 DOI: 10.11152/mu-4439
Daniel Wastl, Michael Blaivas, Rudolf Horn, Guido Michels, Armin Seibel, Simone Schwarz, Beatrice Hoffmann Hoffmann, Oliver Hoffmann, Dieter Von Ow, Christoph F Dietrich

Point of Care Ultrasound (POCUS) can be useful as a tool before, during and after the performance of cardiopulmonary resuscitation (CPR). Before or after resuscitation it can help with monitoring unstable hemodynamics, has the potential to identify reversible causes if patient deteriorates. During resuscitation POCUS can help detect potentially treatable causes of the cardiac arrest. Performance of POCUS while resuscitation requires experienced sonologists and a good team structure to embed the examination in advanced cardiovascular life support (ACLS) algorithms. This article gives an overview and tips about how to detect potential reversible causes of patient deterioration in all three phases of CPR. We describe some special situations in which resuscitation could take place. Further we give a comment about sonographic education of physicians and nonacademic medical staf.

在进行心肺复苏(CPR)之前、期间和之后,护理点超声(POCUS)都是非常有用的工具。在复苏前后,它有助于监测不稳定的血流动力学,并有可能在患者病情恶化时找出可逆的原因。在复苏过程中,POCUS 可帮助检测心脏骤停的潜在治疗原因。在复苏过程中进行 POCUS 需要经验丰富的超声专家和良好的团队结构,以便将检查纳入高级心血管生命支持 (ACLS) 算法。本文概述了如何在心肺复苏的所有三个阶段检测患者病情恶化的潜在可逆原因,并提供了相关提示。我们描述了一些可以进行复苏的特殊情况。此外,我们还对医生和非学术医务人员的声像图教育发表了评论。
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引用次数: 0
Ultrasound of the spleen - an update on measurements, reference values, and influencing factors. A systematic review. 脾脏超声 - 测量、参考值和影响因素的最新进展。系统综述。
Pub Date : 2024-09-22 DOI: 10.11152/mu-4436
Claudia Lucius, Jennifer Meier, Anna Gschmack, Constantinos Zervides, Christian Jenssen, Yi Dong, Ole Graumann, Marieke Petry, Christoph F Dietrich

Reliable and reproducible measurement methods have been established, and reference values are used in almost all scientific disciplines. The knowledge of reference values is crucial to distinguish physiological from pathological processes and, therefore, subsequently, for the clinical management of patients. The image storage and documentation of measurements and normal findings should be part of quality assurance in imaging. This paper aims to review published literature and provide current knowledge of sonographic measurements of the spleen, examination techniques, and knowledge of normal values with their possible clinical implications. Moreover, the role of clinical influencing factors such as age, gender, or ethnicity is also analyzed.

可靠、可重复的测量方法已经确立,参考值几乎用于所有科学学科。参考值的知识对区分生理和病理过程至关重要,因此对患者的临床治疗也至关重要。图像存储和记录测量结果和正常结果应成为成像质量保证的一部分。本文旨在回顾已发表的文献,提供有关脾脏超声测量、检查技术、正常值及其可能的临床意义的最新知识。此外,本文还分析了年龄、性别或种族等临床影响因素的作用。
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引用次数: 0
期刊
Medical ultrasonography
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