W. J. Adie and his "pyknolepsy," a century ago.

IF 0.3 3区 哲学 Q3 HISTORY & PHILOSOPHY OF SCIENCE Journal of the History of the Neurosciences Pub Date : 2024-04-01 Epub Date: 2023-11-08 DOI:10.1080/0964704X.2023.2266456
Mervyn J Eadie
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Abstract

On November 8, 1923, William John Adie described an unusual disorder to the Section of Neurology of the Royal Society of Medicine. The condition comprised frequent momentary stereotyped impairments of consciousness that occurred in children, did not respond to antiseizure medications, and did not develop into epilepsy, as that term was then commonly understood, since no convulsive seizures occurred. After some time, the episodes terminated spontaneously, leaving the sufferer unhandicapped and neurologically intact. Almost certainly, Adie had described the present-day entity of childhood absence epilepsy. He termed it "pyknolepsy," knowing that the name "pyknolepsie" had been used for a similar disorder in Germany from 1916 onwards, though not reported elsewhere. Following Adie's account, published in 1924, reports of the disorder appeared in the English and French-language literature and continued to be published in German. It became increasingly accepted that pyknolepsy was a form of epilepsy that was part of Lennox's petit mal triad. The word pyknolepsy itself never became widely used and is now largely forgotten. Adie never took up the topic in print again. However, he had awakened English-language readers to one component in a broadening of the concept of what constituted epilepsy.

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一个世纪前,W·J·阿迪和他的“侏儒症”。
1923年11月8日,威廉·约翰·阿迪向英国皇家医学会神经病学分会描述了一种不寻常的疾病。这种情况包括儿童经常出现的短暂的刻板意识障碍,对抗癫痫药物没有反应,也没有发展成癫痫,因为没有发生抽搐性癫痫。一段时间后,发作自发终止,使患者没有症状,神经系统完好无损。几乎可以肯定的是,阿迪描述了当今儿童缺席癫痫的真实情况。他将其称为“侏儒症”,因为他知道从1916年起,“侏儒症“这个名字在德国就被用于治疗类似的疾病,尽管其他地方没有报道。根据Adie于1924年发表的描述,有关这种疾病的报道出现在英语和法语文献中,并继续以德语发表。人们越来越普遍地认为,结节性癫痫是一种癫痫,是Lennox小三合会的一部分。pyknolepsy这个词本身从未被广泛使用,现在基本上被遗忘了。阿迪再也没有在报纸上提到这个话题。然而,他唤醒了英语读者,让他们认识到癫痫概念的一个组成部分。
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来源期刊
Journal of the History of the Neurosciences
Journal of the History of the Neurosciences 社会科学-科学史与科学哲学
CiteScore
1.00
自引率
20.00%
发文量
55
审稿时长
>12 weeks
期刊介绍: The Journal of the History of the Neurosciences is the leading communication platform dealing with the historical roots of the basic and applied neurosciences. Its domains cover historical perspectives and developments, including biographical studies, disorders, institutions, documents, and instrumentation in neurology, neurosurgery, neuropsychiatry, neuroanatomy, neurophysiology, neurochemistry, neuropsychology, and the behavioral neurosciences. The history of ideas, changes in society and medicine, and the connections with other disciplines (e.g., the arts, philosophy, psychology) are welcome. In addition to original, full-length papers, the journal welcomes informative short communications, letters to the editors, book reviews, and contributions to its NeuroWords and Neurognostics columns. All manuscripts are subject to initial appraisal by an Editor, and, if found suitable for further consideration, full- and short-length papers are subject to peer review (double blind, if requested) by at least 2 anonymous referees.
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