{"title":"Bone marrow immune cells stop weight regain.","authors":"Jing Yan, Cheng Hu","doi":"10.1016/j.cmet.2023.10.004","DOIUrl":null,"url":null,"abstract":"<p><p>Weight regain is a major challenge in the long-term management of obesity; however, the underlying mechanisms remain unclear. Zhou et al. found that bone-marrow-derived CD7<sup>+</sup> monocytes respond to fluctuating nutritional stress and suppress weight regain by promoting beige fat thermogenesis.</p>","PeriodicalId":93927,"journal":{"name":"Cell metabolism","volume":"35 11","pages":"1845-1846"},"PeriodicalIF":0.0000,"publicationDate":"2023-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Cell metabolism","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1016/j.cmet.2023.10.004","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 1
Abstract
Weight regain is a major challenge in the long-term management of obesity; however, the underlying mechanisms remain unclear. Zhou et al. found that bone-marrow-derived CD7+ monocytes respond to fluctuating nutritional stress and suppress weight regain by promoting beige fat thermogenesis.
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