{"title":"Synthetic Biology: Major Principles and Current Trends of Development in Russia","authors":"M. V. Patrushev, A. A. Borisova, Z. B. Namsaraev","doi":"10.1134/S2635167623700210","DOIUrl":null,"url":null,"abstract":"<div><p>Synthetic biology is an interdisciplinary field of science and technology aimed at developing methods and approaches to design and construct living systems at different levels of their organization based on engineering principles. The work describes the main characteristics of synthetic biology, one of the most promising and interesting directions in the biological sciences. We review in detail the modern methods and approaches used by synthetic biologists to create new types of biological systems, their functional units, and components. Particular attention is paid to actions to stimulate the development of synthetic biology in Russia. This requires wider application of the process approach and engineering principles, the formation of a centralized depository of functional genetic elements, standardization of the components and procedures used, deeper analysis of the genomes of organisms from bioresource collections and the subsequent storage of information in the National Genomic Information Database, and intensification of the development of equipment for high-throughput DNA synthesis.</p></div>","PeriodicalId":716,"journal":{"name":"Nanotechnologies in Russia","volume":null,"pages":null},"PeriodicalIF":0.8000,"publicationDate":"2023-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nanotechnologies in Russia","FirstCategoryId":"1085","ListUrlMain":"https://link.springer.com/article/10.1134/S2635167623700210","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Engineering","Score":null,"Total":0}
引用次数: 0
Abstract
Synthetic biology is an interdisciplinary field of science and technology aimed at developing methods and approaches to design and construct living systems at different levels of their organization based on engineering principles. The work describes the main characteristics of synthetic biology, one of the most promising and interesting directions in the biological sciences. We review in detail the modern methods and approaches used by synthetic biologists to create new types of biological systems, their functional units, and components. Particular attention is paid to actions to stimulate the development of synthetic biology in Russia. This requires wider application of the process approach and engineering principles, the formation of a centralized depository of functional genetic elements, standardization of the components and procedures used, deeper analysis of the genomes of organisms from bioresource collections and the subsequent storage of information in the National Genomic Information Database, and intensification of the development of equipment for high-throughput DNA synthesis.
期刊介绍:
Nanobiotechnology Reports publishes interdisciplinary research articles on fundamental aspects of the structure and properties of nanoscale objects and nanomaterials, polymeric and bioorganic molecules, and supramolecular and biohybrid complexes, as well as articles that discuss technologies for their preparation and processing, and practical implementation of products, devices, and nature-like systems based on them. The journal publishes original articles and reviews that meet the highest scientific quality standards in the following areas of science and technology studies: self-organizing structures and nanoassemblies; nanostructures, including nanotubes; functional and structural nanomaterials; polymeric, bioorganic, and hybrid nanomaterials; devices and products based on nanomaterials and nanotechnology; nanobiology and genetics, and omics technologies; nanobiomedicine and nanopharmaceutics; nanoelectronics and neuromorphic computing systems; neurocognitive systems and technologies; nanophotonics; natural science methods in a study of cultural heritage items; metrology, standardization, and monitoring in nanotechnology.