Synthetic Biology: Major Principles and Current Trends of Development in Russia

IF 0.8 Q3 Engineering Nanotechnologies in Russia Pub Date : 2023-09-19 DOI:10.1134/S2635167623700210

M. V. Patrushev, A. A. Borisova, Z. B. Namsaraev

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Abstract

Synthetic biology is an interdisciplinary field of science and technology aimed at developing methods and approaches to design and construct living systems at different levels of their organization based on engineering principles. The work describes the main characteristics of synthetic biology, one of the most promising and interesting directions in the biological sciences. We review in detail the modern methods and approaches used by synthetic biologists to create new types of biological systems, their functional units, and components. Particular attention is paid to actions to stimulate the development of synthetic biology in Russia. This requires wider application of the process approach and engineering principles, the formation of a centralized depository of functional genetic elements, standardization of the components and procedures used, deeper analysis of the genomes of organisms from bioresource collections and the subsequent storage of information in the National Genomic Information Database, and intensification of the development of equipment for high-throughput DNA synthesis.

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合成生物学:俄罗斯的主要原理和当前发展趋势

合成生物学是一个跨学科的科学和技术领域，旨在根据工程原理开发设计和构建不同组织层次的生命系统的方法和途径。该工作描述了合成生物学的主要特点，合成生物学是生物科学中最有前途和最有趣的方向之一。我们详细回顾了合成生物学家用于创建新型生物系统及其功能单元和组件的现代方法和途径。特别注意刺激俄罗斯合成生物学发展的行动。这需要更广泛地应用过程方法和工程原理，形成一个功能遗传元素的集中存储库，标准化所使用的组件和程序，对生物资源收集的生物体基因组进行更深入的分析，并随后将信息存储在国家基因组信息数据库中，并加强高通量DNA合成设备的开发。

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来源期刊

Nanotechnologies in Russia NANOSCIENCE & NANOTECHNOLOGY-

CiteScore

1.20

自引率

0.00%

发文量

期刊介绍： Nanobiotechnology Reports publishes interdisciplinary research articles on fundamental aspects of the structure and properties of nanoscale objects and nanomaterials, polymeric and bioorganic molecules, and supramolecular and biohybrid complexes, as well as articles that discuss technologies for their preparation and processing, and practical implementation of products, devices, and nature-like systems based on them. The journal publishes original articles and reviews that meet the highest scientific quality standards in the following areas of science and technology studies: self-organizing structures and nanoassemblies; nanostructures, including nanotubes; functional and structural nanomaterials; polymeric, bioorganic, and hybrid nanomaterials; devices and products based on nanomaterials and nanotechnology; nanobiology and genetics, and omics technologies; nanobiomedicine and nanopharmaceutics; nanoelectronics and neuromorphic computing systems; neurocognitive systems and technologies; nanophotonics; natural science methods in a study of cultural heritage items; metrology, standardization, and monitoring in nanotechnology.