Understanding How Minerals Contribute to Optimal Immune Function.

IF 3.5 3区 医学 Q2 IMMUNOLOGY Journal of Immunology Research Pub Date : 2023-11-01 eCollection Date: 2023-01-01 DOI:10.1155/2023/3355733
Alina Stefanache, Ionut-Iulian Lungu, Ioan-Adrian Butnariu, Gabriela Calin, Cristian Gutu, Constantin Marcu, Carmen Grierosu, Elena Roxana Bogdan Goroftei, Letitia-Doina Duceac, Marius Gabriel Dabija, Florina Popa, Daniela Damir
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Abstract

Sufficient mineral supply is vital not only for the innate immune system but also for the components of the adaptive immune defense, which encompass defense mechanisms against pathogens and the delicate balance of pro- and anti-inflammatory regulation in the long term. Generally, a well-balanced diet is capable of providing the necessary minerals to support the immune system. Nevertheless, specific vulnerable populations should be cautious about obtaining adequate amounts of minerals such as magnesium, zinc, copper, iron, and selenium. Inadequate levels of these minerals can temporarily impair immune competence and disrupt the long-term regulation of systemic inflammation. Therefore, comprehending the mechanisms and sources of these minerals is crucial. In exceptional circumstances, mineral deficiencies may necessitate supplementation; however, excessive intake of supplements can have adverse effects on the immune system and should be avoided. Consequently, any supplementation should be approved by medical professionals and administered in recommended doses. This review emphasizes the crucial significance of minerals in promoting optimal functioning of the immune system. It investigates the indispensable minerals required for immune system function and the regulation of inflammation. Moreover, it delves into the significance of maintaining an optimized intake of minerals from a nutritional standpoint.

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了解矿物质如何促进最佳免疫功能。
充足的矿物质供应不仅对先天免疫系统至关重要,而且对适应性免疫防御的组成部分也至关重要,适应性免疫防御包括对抗病原体的防御机制以及长期促炎和抗炎调节的微妙平衡。一般来说,均衡的饮食能够提供必要的矿物质来支持免疫系统。尽管如此,特定的弱势群体应谨慎获取足量的矿物质,如镁、锌、铜、铁和硒。这些矿物质水平不足会暂时损害免疫能力,并破坏系统炎症的长期调节。因此,了解这些矿物的机制和来源至关重要。在特殊情况下,矿物质缺乏可能需要补充;然而,过量摄入补充剂会对免疫系统产生不良影响,应该避免。因此,任何补充剂都应得到医疗专业人员的批准,并按推荐剂量服用。这篇综述强调了矿物质在促进免疫系统最佳功能方面的重要意义。它研究了免疫系统功能和炎症调节所需的不可或缺的矿物质。此外,它还从营养的角度探讨了保持矿物质最佳摄入量的重要性。
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来源期刊
CiteScore
6.90
自引率
2.40%
发文量
423
审稿时长
15 weeks
期刊介绍: Journal of Immunology Research is a peer-reviewed, Open Access journal that provides a platform for scientists and clinicians working in different areas of immunology and therapy. The journal publishes research articles, review articles, as well as clinical studies related to classical immunology, molecular immunology, clinical immunology, cancer immunology, transplantation immunology, immune pathology, immunodeficiency, autoimmune diseases, immune disorders, and immunotherapy.
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