Effect of Sinovac or Biontech Vaccination on Mortality in COVID-19 Patients in The Intensive Care Unit

Abstract

Introduction: COVID-19 infection has spread with the development of the pandemic and is transmitted by respiratory droplets. The level of protection of vaccines administered together with the COVID-19 vaccine is the subject of research. We aimed to examine intensive care patients with Sinovac and Biontech vaccines. Material and Method: After the approval of the ethics committee, 45 patient data were included in our study. Vaccination status in intensive care units was examined and patients were grouped into Sinovac and Biontech. Age, sex, comorbid conditions, and mortality rates were compared statistically. With this comparison, the effects on mortality and clinical features were evaluated. Results: Forty-five patients between March 31 and December 31, 2021 were included in the study. In these patients, patients who received 2 doses of vaccine in the period before hospitalization according to the intensive care evaluation criteria were examined. Mortality rates were higher in patients who received 2 doses of Sinovac vaccine in patients hospitalized in the intensive care unit compared to those who received 2 doses of Biontech vaccine. Conclusion: It was observed that the vaccination status of patients who were vaccinated with COVID-19 and taken to the intensive care unit affected mortality. Studies with larger numbers of patients are needed.