Nanoparticles Formed by Complexation of Poly-γ-glutamic Acid and Lead Ions

M. Bodnár, A. Kjøniksen, J. Hartmann, L. Daroczi, B. Nyström, J. Borbély
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引用次数: 2

Abstract

The present investigation describes the preparation and characterization of novel biodegradable nanoparticles based on complexation of poly-gamma-glutamic acid (γ-PGA) with bivalent lead ions. The prepared nanosystems were stable in aqueous media at low pH, neutral and mild alkaline conditions. The solubility and size of these nanoparticles in the dried and swollen states will be described and discussed. The correlation of size of particles, pH of the solutions, concentration and the ratio of compound polyelectrolytes have been studied. It was found, that the size of individual particles was in the range of 40-100 nm measured by TEM. The low and high pH values in mixtures with high concentrations of γ-PGA and Pb ions favored the growth of large complexes. The γ-PGA nanoparticles, which are from a biodegradable biomaterial with high flocculating and heavy metal binding activity, may be useful for various water treatment applications in aqueous media.
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聚γ-谷氨酸与铅离子络合形成的纳米颗粒
本研究描述了一种新型可生物降解纳米粒子的制备和表征,该纳米粒子是基于多γ-谷氨酸(γ-PGA)与二价铅离子的络合。制备的纳米体系在低pH、中性和温和碱性条件下均稳定存在。这些纳米颗粒在干燥和膨胀状态下的溶解度和大小将被描述和讨论。研究了颗粒大小、溶液pH值、浓度和复合电解质配比的关系。结果表明,透射电镜测得的单个颗粒尺寸在40 ~ 100 nm之间。在高pH和低pH浓度的γ-PGA和Pb离子混合物中,有利于大型配合物的生长。γ-PGA纳米颗粒是由具有高絮凝性和重金属结合活性的可生物降解生物材料制备而成,可用于各种水介质的水处理。
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