Impact of antimicrobial resistance on health and economy: A comprehensive review

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Abstract

Antibiotics have historically revolutionized medical science; however, the rise of multidrug-resistant pathogenic bacteria puts their worth at risk. The problem of antibiotic resistance has been attributed to both the excessive use of already available drugs and the absence of newer treatments as a result of stringent regulatory requirements and weakened corporate incentives. Resistant infections often need more comprehensive and costly treatments, resulting in longer hospital admissions, higher healthcare costs, and a larger demand for specialized healthcare resources. The expenses are exacerbated by the need for new antimicrobial drug research and development, which is becoming more complex and expensive as a result of resistance mechanisms. Comprehensive efforts are needed to limit the rate of resistance development and include research into new bacteria, resistance mechanisms, and antimicrobial medications. Multidisciplinary approaches are required in the sectors of agriculture, the environment, and healthcare. Probiotics, antibodies, and vaccines are a few examples of progressive complementary therapies that have shown promising outcomes in research and may one day serve as preventive or supplementary treatments. The purpose of this review article is to give an in-depth review of the influence of antibiotic resistance on both the health of individuals and economic stability.
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抗微生物药物耐药性对健康和经济的影响:综述
抗生素在历史上彻底改变了医学;然而,耐多药致病菌的增加使它们的价值面临风险。抗生素耐药性问题归因于过度使用现有药物,以及由于严格的监管要求和企业激励减弱而缺乏新的治疗方法。耐药感染通常需要更全面、更昂贵的治疗,从而导致住院时间更长、医疗费用更高以及对专业医疗资源的更大需求。由于耐药机制的原因,新的抗微生物药物研究和开发正变得更加复杂和昂贵,这一需求加剧了费用。需要综合努力来限制耐药性的发展速度,并包括对新细菌、耐药机制和抗微生物药物的研究。农业、环境和医疗保健部门需要多学科方法。益生菌、抗体和疫苗是进步的补充疗法的几个例子,在研究中显示出有希望的结果,可能有一天作为预防或补充治疗。这篇综述文章的目的是对抗生素耐药性对个人健康和经济稳定的影响进行深入的综述。
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