Case Report: Generalize Pustular Psoriasis Pregnancy (GPPP) in Multiple Pregnancies

IF 0.2 Q4 PHARMACOLOGY & PHARMACY Asian Journal of Pharmaceutical Research and Health Care Pub Date : 2022-11-29 DOI:10.55561/ajhr.v1i3.34
Probo Yudha Pratama Putra, Aida Musyarrofah, D. Pravitasari, Yulia Nugrahanitya
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Abstract

Introduction: General Pustular psoriasis pregnancy (GPPP) is a dermatosis that occurs in pregnancy and requires serious management to reduce the risk of mortality and morbidity in both pregnancy mother and fetus. This disorder is also called impetigo herpetiform. Case Presentation: We report a woman with multiple pregnancies, G3P2A0 at 21 weeks gestation, with well-defined erythematous macules 5–10 cm in diameter, partly coalescent, with thick scales, and 0.1–0.2 cm diameter pustules and leukocytosis. Patients receive 1 mg of dexamethasone every morning, clobetasol cream 0.05% twice daily, gentamycin 0.1% three times daily, and 3% salicylic acid cream, while to avoid the emergence of preeclampsia aspirin is given at a low dose of 75 mg/day, and we use vipalbumin to treat hypoalbuminemia. The patient gave birth to premature twins by normal delivery. Conclusion: GPPP is a rare dermatosis with serious risks and consequences for both mother and child. Supportive management is needed to maintain pregnancy and prevent complications.
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病例报告:妊娠脓疱性银屑病(GPPP)在多胎妊娠中的普遍性
妊娠期全身性脓疱性牛皮癣(GPPP)是一种发生在妊娠期的皮肤病,需要严格的管理以降低孕妇和胎儿的死亡率和发病率。这种疾病也被称为疱疹性脓疱疮。病例介绍:我们报告一名多胎妊娠妇女,妊娠21周,G3P2A0,有直径5-10厘米的明确红斑,部分为聚白色,鳞片厚,直径0.1-0.2厘米的脓疱和白细胞增多。患者每天早晨给予地塞米松1mg,氯倍他索乳膏0.05%,每日2次,庆大霉素0.1%,每日3次,3%水杨酸乳膏,同时为避免先兆子痫的出现给予阿司匹林低剂量75mg /天,我们使用静脉白蛋白治疗低白蛋白血症。病人正常分娩生下一对早产双胞胎。结论:GPPP是一种罕见的皮肤病,对母亲和孩子都有严重的风险和后果。需要支持性管理来维持妊娠并预防并发症。
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