Indocyanine green angiographic documentation of regression of polypoidal lesions after brolucizumab injection in polypoidal choroidal vasculopathy

Abstract

An elderly male presented with complaints of decrease in vision in the left eye since 1 week. He had a recurrent submacular hemorrhage secondary to polypoidal choroidal vasculopathy (PCV) and was treated with intravitreal brolucizumab. There was complete resolution of subretinal fluid and improvement in visual acuity to 20/20 on follow-up. Indocyanine green angiography at 1 year showed complete regression of polypoidal lesions. This case report highlights the role of brolucizumab as an effective treatment option in resistant PCV and its role in regression of polypoidal lesions in PCV.