{"title":"Dietary Anthocyanins- Smart Molecules with Chemo Preventive and Chemotherapeutic Activity","authors":"Dharmawansa K V Surangi ","doi":"10.19080/omcij.2020.09.555779","DOIUrl":null,"url":null,"abstract":"Cancer is the second leading cause of death in global and has a major impact on human wellbeing. Recently, dietary interventions in cancer prevention and use of plant secondary metabolites in cancer therapies have been received a considerable attention. Anthocyanin, a group of flavonoids have investigated extensively for its chemopreventive and chemotherapeutic activity against the several types of cancers. Anthocyanin possess strong antioxidant activity. In addition to that, anthocyanin have shown the anti-inflammatory, anti-proliferative, apoptotic, and anti-tumorigenic properties in both in vitro and in vivo. This mini review summarizes the potential molecular mechanisms and anti-cancer activity of anthocyanin towards the breast, lung, and colorectal cancer.","PeriodicalId":19547,"journal":{"name":"Organic & Medicinal Chemistry International Journal","volume":"73 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2020-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"2","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Organic & Medicinal Chemistry International Journal","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.19080/omcij.2020.09.555779","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 2
Abstract
Cancer is the second leading cause of death in global and has a major impact on human wellbeing. Recently, dietary interventions in cancer prevention and use of plant secondary metabolites in cancer therapies have been received a considerable attention. Anthocyanin, a group of flavonoids have investigated extensively for its chemopreventive and chemotherapeutic activity against the several types of cancers. Anthocyanin possess strong antioxidant activity. In addition to that, anthocyanin have shown the anti-inflammatory, anti-proliferative, apoptotic, and anti-tumorigenic properties in both in vitro and in vivo. This mini review summarizes the potential molecular mechanisms and anti-cancer activity of anthocyanin towards the breast, lung, and colorectal cancer.