Dietary Anthocyanins- Smart Molecules with Chemo Preventive and Chemotherapeutic Activity

Dharmawansa K V Surangi 
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引用次数: 2

Abstract

Cancer is the second leading cause of death in global and has a major impact on human wellbeing. Recently, dietary interventions in cancer prevention and use of plant secondary metabolites in cancer therapies have been received a considerable attention. Anthocyanin, a group of flavonoids have investigated extensively for its chemopreventive and chemotherapeutic activity against the several types of cancers. Anthocyanin possess strong antioxidant activity. In addition to that, anthocyanin have shown the anti-inflammatory, anti-proliferative, apoptotic, and anti-tumorigenic properties in both in vitro and in vivo. This mini review summarizes the potential molecular mechanisms and anti-cancer activity of anthocyanin towards the breast, lung, and colorectal cancer.
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膳食花青素-具有化学预防和化学治疗活性的智能分子
癌症是全球第二大死亡原因,对人类健康产生重大影响。近年来,饮食干预在癌症预防和利用植物次生代谢物在癌症治疗中得到了相当大的关注。花青素是一类黄酮类化合物,其对多种癌症的化学预防和化学治疗作用已被广泛研究。花青素具有很强的抗氧化活性。此外,花青素在体外和体内均显示出抗炎、抗增殖、细胞凋亡和抗肿瘤的特性。本文就花青素在乳腺癌、肺癌和结直肠癌中的潜在分子机制和抗癌作用作一综述。
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