Manufacturing Process Development of Health Supplement Containing Water Hyacinth (Eichhornia crassipes) Extract

D. Widiputri, Quincy Juventinus, Silvya Yusri, F. I. Pandiangan, Jimmy
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Abstract

Water hyacinth (Eichhornia crassipes), WH, is an aquatic plant that usually lives on the surface of lakes, marshes or rivers and often considered to be a weed that brings many negative impacts for the aquatic ecosystem. Previous research has proven the presence of antioxidant activity in the extract of this plant, which can be very beneficial for human health. However, to commercially utilize the extract of this plant, several steps must be thoroughly studied and prepared. This work was aimed at the development of manufacturing process to produce health product containing water hyacinth extract, where all aspects including the product safety, the availability of the main raw material, the proper formula of the product, the potential production capacity and the estimation of product quality in terms of the antioxidant activity were simulated. Market research conducted prior to the process development showed that tablet form was preferred by most respondents. The material balance calculation completed following the process development showed a potential production capacity of 812 tablets per hour by utilizing 30 kg/h of fresh WH leaves, with an expected antioxidant IC50 value of the product of 480.24 ppm, which should be very competitive when compared with other herbal supplements that are already commercially marketed.
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含水葫芦提取物保健品的生产工艺开发
水葫芦(Eichhornia crassipes), WH,是一种水生植物,通常生活在湖泊、沼泽或河流的表面,通常被认为是一种对水生生态系统带来许多负面影响的杂草。以前的研究已经证明这种植物的提取物具有抗氧化活性,这对人体健康非常有益。然而,为了商业利用这种植物的提取物,必须彻底研究和准备几个步骤。本研究旨在开发含水葫芦提取物保健品的生产工艺,对产品的安全性、主要原料的可得性、产品的合理配方、潜在的生产能力以及产品抗氧化活性的质量评价等方面进行了模拟。在工艺开发之前进行的市场研究表明,大多数受访者更喜欢片剂形式。在工艺开发之后完成的物质平衡计算显示,利用30 kg/h的新鲜WH叶,每小时的潜在生产能力为812片,产品的抗氧化剂IC50值预计为480.24 ppm,与已经商业化销售的其他草药补充剂相比,这应该是非竞争性的。
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