Isolation and characterization of microcrystalline cellulose obtained from palm nut ( Elaeis guineensis ) fibres

F. Ohwoavworhua, I. Uya, O. Kunle
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引用次数: 2

Abstract

In this study, microcrystalline cellulose, coded MCC-PNF, was obtained from palm nut ( Elaeis guineensis ) fibres. MCC-PNF was examined for its physicochemical and powder properties. The powder properties of MCC-PNF were compared to those of the best commercial microcrystalline cellulose grade, Avicel PH 101. The extraction yield of MCC-PNF was approximately 8% w/w. The cellulose material was composed of irregularly shaped fibrous cellulose particles and has a moisture content of 5.6% and total ash of 0.21%. The true density was 1.54 g/cm 3 . The flow indices showed that MCC-PNF flowed poorly. The hydration and swelling capacities were 3.82 and 56.8% respectively. The study revealed that the cellulose material comparesfavourably with Avicel PH 101 and conformed to official requirements specified in the British Pharmacopoeia and Handbook of Pharmaceutical Excipients for microcrystalline cellulose. Keywords : palm nut fibres, microcrystalline cellulose, isolation, characterization Journal of Pharmaceutical and Allied Sciences Vol. 3(1) 2006: 255-262
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棕榈仁纤维微晶纤维素的分离与特性研究
在本研究中,从棕榈坚果(Elaeis guineensis)纤维中获得微晶纤维素,编码MCC-PNF。对MCC-PNF的理化性能和粉末性能进行了测试。将MCC-PNF的粉末性能与最佳商业微晶纤维素等级Avicel PH 101进行了比较。MCC-PNF的提取率约为8% w/w。该纤维素材料由不规则形状的纤维纤维素颗粒组成,含水率为5.6%,总灰分为0.21%。真实密度为1.54 g/ cm3。流动指标显示MCC-PNF流动较差。水化率为3.82%,溶胀率为56.8%。研究表明,纤维素材料与Avicel PH 101相当,符合英国药典和药用辅料手册中关于微晶纤维素的官方要求。关键词:棕榈坚果纤维,微晶纤维素,分离,表征医药与相关科学杂志Vol. 3(1) 2006: 255-262
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