Study into the Efficacy of the Epophen Substance in Normobaric Hypoxia

K. Ostrenko, A. Ovcharova, O. P. Yegorova
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Abstract

Hypoxia is associated with reduced oxygen levels in the body, individual organs, or tissues. Hypoxia is the most common cause of cell damage, emerging under a lack of oxygen in the inhaled air, blood (hypoxemia), or tissues (violations of tissue respiration). When the strength or duration of hypoxic exposure exceeds the adaptive capabilities of the body, an organ, or a tissue, irreversible changes may develop. Resistance to hypoxia can be enhanced by pharmacological agents that improve oxygen delivery and/or the effectiveness of its use. This study was conducted to determine the antihypoxic effect of the Epophen drug. Epophen was found to exhibit a pronounced antihypoxic effect, with the efficacy varying from 24 to 89% depending on the drug dose and hypoxia type.
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Epophen物质在常压缺氧中的作用研究
缺氧与体内、个别器官或组织的含氧量降低有关。缺氧是细胞损伤最常见的原因,在吸入空气、血液(低氧血症)或组织(违反组织呼吸)缺氧的情况下出现。当低氧暴露的强度或持续时间超过身体、器官或组织的适应能力时,可能会发生不可逆转的变化。抗缺氧能力可以通过改善氧气输送和/或其使用效果的药物来增强。本研究旨在确定Epophen药物的抗缺氧作用。Epophen被发现具有明显的抗缺氧作用,根据药物剂量和缺氧类型的不同,其疗效从24%到89%不等。
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