Overview of COVID-19 As Global Pandemic

Musmade Nirmala Ashok, Kakade Swati Babasahe, M. Sitaram, Shaikh Sabhafarin Hasin, Matsagar Aishwarya Rajendra, Aghade Karveer
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Abstract

Beginning of the new decade was highlighted with the global outbreak of Coronavirus disease-19 (COVID-19). It is a kind of viral pneumonia which is caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), a new strain of Coronavirus. This outbreak of pneumonia with unknown etiology was thought to have originated from the Huanan seafood market and was reported firstly at Wuhan, in China. On 31 January 2020, the World Health Organization (WHO) announced that COVID-19 was listed as the Public Health Emergency of International Concern (PHEIC).The virus was named as COVID-19 on 11th February, 2020 by WHO. As it has affected the whole world, it was declared as global pandemic by WHO. SARS-CoV-2 is the betacoronavirus with presence of different proteins which helps in attachment, penetration, biosynthesis, maturation and release of newly synthesized virion particles in the host body and infect the host. COVID-19 is contagious and primarily spreads through the respiratory tract, by droplets, respiratory secretions, and direct contact. As no vaccine or drug molecule are available yet, breaking the chain, enhancing an individual's body immunity, identifying the infection early and timely medical care are the best ways to prevent COVID-19 infection. Along with Allopathy medicines, Ayurveda, Unani and Homeopathy medicines are used as add-ons to treat the disease. Thus, taking into consideration this global threat this review focuses on origin, morphology of SARS-CoV-2, pathogenesis, role of Ayurveda, Unani, Homeopathy and Allopathy in treatment of COVID-19 and the current scenario of vaccines against COVID-19.
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COVID-19全球大流行概述
新十年伊始,全球爆发了冠状病毒病-19 (COVID-19)。它是一种由新型冠状病毒株——严重急性呼吸综合征冠状病毒-2 (SARS-CoV-2)引起的病毒性肺炎。这次病因不明的肺炎疫情被认为起源于华南海鲜市场,并首先在中国武汉报告。2020年1月31日,世界卫生组织(世卫组织)宣布将COVID-19列为国际关注的突发公共卫生事件。世卫组织于2020年2月11日将该病毒命名为COVID-19。由于影响全球,世卫组织宣布其为全球大流行。SARS-CoV-2是一种贝塔冠状病毒,它含有不同的蛋白质,有助于在宿主体内附着、渗透、生物合成、成熟和释放新合成的病毒粒子,并感染宿主。COVID-19具有传染性,主要通过呼吸道、飞沫、呼吸道分泌物和直接接触传播。由于目前还没有疫苗或药物分子,打破病毒链、增强个人免疫力、及早发现感染并及时就医是预防COVID-19感染的最佳途径。与对抗疗法药物一起,阿育吠陀、乌纳尼和顺势疗法药物被用作治疗这种疾病的附加药物。因此,考虑到这一全球性威胁,本综述侧重于SARS-CoV-2的起源、形态、发病机制、阿育吠陀、乌纳尼、顺势疗法和对抗疗法在治疗COVID-19中的作用以及COVID-19疫苗的现状。
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