Application of Biotechnology towards Diagnosis and Treatment in Veterinary Medicine in Africa: Potentials and Future Developments

Mohammed Br, Malang Sk, S. Mailafia, Agbede Ris
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引用次数: 7

Abstract

Biotechnology is an already established technique in several areas of medicine, but its application in the field of veterinary medicine has only started to emerge with the potential to revolutionize veterinary practice. This paper therefore reviews the potential applications of biotechnology in veterinary medicine towards diagnosis and treatment in Africa which includes; molecular gene cloning, production of recombinant biotechnology derived vaccines, application of polymerase chain reaction (PCR), Real time polymerase chain reaction (RT-PCR), Polymerase chain reaction - restriction fragment length polymorphism (PCR-RFLP) and Bioinformatics to diagnosis of infectious and parasitic diseases , gene therapy, disease diagnosis, treatment delivery systems and many more. These components occur in other parts of the world and are therefore presumed to be consolidated into the African delivery framework as a private enterprise in a foreseeable future. Whilst it is sensible to postulate that biotechnology application and its peculiar evolution will imminently transform veterinary medicine, there is immense treat, amidst stakeholders in the industry, about food health and safety and other civil and ethical concerns which can hinder this novel scientific breakthrough. The ethical concerns which include; theory of the Three Rs (Reduction of animal population, Refinement of enactments and farm managements to curtail affliction and despair, Replacement of animals with non-animal surrogate wherever necessary. Limitations regarding the application to veterinary practices are extensively discussed. This review has implication on the future of revolutionalisation of veterinary practice and increase in animal protein source for human consumption
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生物技术在非洲兽医诊断和治疗中的应用:潜力和未来发展
生物技术在医学的几个领域已经是一项成熟的技术,但它在兽医学领域的应用才刚刚开始出现,具有彻底改变兽医学实践的潜力。因此,本文综述了生物技术在非洲兽医诊断和治疗方面的潜在应用,其中包括;分子基因克隆、重组生物技术衍生疫苗的生产、聚合酶链反应(PCR)、实时聚合酶链反应(RT-PCR)、聚合酶链反应-限制性片段长度多态性(PCR- rflp)和生物信息学在传染病和寄生虫病诊断、基因治疗、疾病诊断、治疗递送系统等方面的应用。这些组成部分在世界其他地区也有,因此可以推定在可预见的将来将作为私营企业并入非洲执行框架。假设生物技术的应用及其独特的进化将立即改变兽医学是明智的,但在该行业的利益相关者中,关于食品健康和安全以及其他民事和伦理问题的巨大对待可能会阻碍这一新的科学突破。伦理问题包括:三r理论(减少动物数量,完善法规和农场管理以减少痛苦和绝望,必要时用非动物替代品代替动物)。关于应用于兽医实践的限制进行了广泛的讨论。这篇综述对未来兽医实践的革命和人类消费动物蛋白来源的增加具有启示意义
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