PREPARATION OF ANTISEPTIC HYDROGEL PLATES BASED ON NATURAL POLYSACCHARIDES

І. Dron, N. Bukartyk, M. Bukartyk, D. Ostapiv, V. Samaryk
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Abstract

Using natural polysaccharides, pectin and sodium alginate, hydrogel plates capable of absorbing exudate were obtained. Studies have shown no cytotoxicity of the plate material. In order to create bactericidal therapeutic dressings based on them, the possibility of filling the plates with antiseptics (iodine, betadine, chlorhexidine) was shown and their release dynamics was studied. Studies have shown that the release of iodine from the plate is too fast and can not meet the condition of its prolonged release in contrast to betadine and chlorhexidine.
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天然多糖防腐水凝胶板的制备
以天然多糖、果胶和海藻酸钠为原料,制备了能吸收渗出液的水凝胶板。研究表明,该板材料没有细胞毒性。为了在此基础上制造杀菌治疗敷料,展示了在平板上填充防腐剂(碘、氯他定、氯己定)的可能性,并研究了它们的释放动力学。研究表明,与氯己定、氯他定相比,碘从平板中释放速度过快,不能满足其缓释条件。
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