Ventricular Repolarization Parameters In Hospitalized Patients With COVID-19

Abstract

Objective: Coronavirus disease-2019 (COVID-19) may cause atrial and/or ventricular arrhythmias and sudden cardiac deaths, especially in severe cases. In this study, we aimed to investigate whether COVID-19 affects the ventricular repolarization parameters. Materials and Methods: In this study, 152 hospitalized patients with COVID-19 were included retrospectively. Age and sex-matched 151 healthy subjects were assigned as the control group. QT, QTc, Tpe, Tpe/QT, and Tpe/QTc values of all participants were determined and compared between both groups. The relationship between high sensitive-troponin I (hsTnI) and the parameters mentioned was analyzed using the Spearman correlation test. Results: Mean age, male gender and comorbidity rates were similar in both groups (p>0.05 for each). Heart rate, QTc, Tpe, Tpe/QT, and Tpe/QTc values were higher in the study group (p<0.001 for each). However, QT and QRS values were comparable in both groups (p>0.05 for each). There were positive correlations between hsTnI and QT (rho=0.218, p=0.008), QTc (rho=0.308, p<0.001), Tpe (rho=0.646, p<0.001), Tpe/QT (rho=0.571, p<0.001), and Tpe/QTc (rho=0.608, p<0.001). Conclusion: In patients with COVID-19, QTc, Tpe, Tpe/QT, and Tpe/QTc values are higher than the control group and these parameters correlate positively with hsTnI. Therefore, ECG follow-up may be beneficial in preventing arrhythmic events, especially in patients with acute cardiac injuries. [ FROM AUTHOR] Copyright of Erciyes Medical Journal / Erciyes Tip Dergisi is the property of KARE Publishing and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full . (Copyright applies to all Abstracts.)