Are preoperative monocytes and HDL values ​​an early predictor of recurrence in the surgical ablation treatment of atrial fibrillation?

Muhittin Zafer Samsa, Funda TOR OCAK
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Abstract

Objective: Monocyte HDL (high-density lipoprotein) cholesterol ratio has been accepted as a newly emerging cardiovascular prognostic marker. The aim of this study is to investigate the determinants of monocyte and HDL cholesterol values ​​in the early recurrence of atrial fibrillation (AF) treated with cryoablation and radiofrequency ablation. Materials and Methods: This retrospective study was conducted between September 2006 and July 2014 in the Department of Cardiovascular Surgery, Adana City Hospital, Health Sciences University, including 100 patients who underwent surgical AF ablation with open heart surgery. Logistic regression analysis was used to determine monocytes and HDL cholesterol values, which are among the factors affecting recurrence in the first 3 months postoperatively. Results: 100 patients who underwent surgical ablation together with open heart surgery were evaluated for early postoperative recurrence. According to the logistic regression analysis, the most effective features and measurements for early recurrence were diabetes mellitus (DM), AF duration, left atrial diameter, and low HDL cholesterol and high monocyte values ​​before the procedure. Conclusion: Preoperative low HDL and high monocyte values ​​can be considered as a determining factor for early recurrence in surgical ablation treatment of AF.
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术前单核细胞和HDL值是房颤手术消融治疗中复发的早期预测因子吗?
目的:单核细胞HDL(高密度脂蛋白)胆固醇比率已被公认为一种新兴的心血管预后指标。本研究的目的是探讨单核细胞和高密度脂蛋白胆固醇值在冷冻消融和射频消融治疗心房颤动(AF)早期复发中的决定因素。材料与方法:本回顾性研究于2006年9月至2014年7月在卫生科学大学阿达纳市医院心血管外科进行,包括100例经心内直视手术心房颤动消融的患者。采用Logistic回归分析确定影响术后前3个月复发的因素之一单核细胞和高密度脂蛋白胆固醇值。结果:对100例行外科消融联合心内直视手术的患者进行术后早期复发评估。根据logistic回归分析,早期复发最有效的特征和指标是术前糖尿病(DM)、房颤持续时间、左房内径、低高密度脂蛋白胆固醇和高单核细胞值。结论:术前低HDL和高单核细胞值可被认为是AF手术消融治疗早期复发的决定因素。
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