Lithium therapy and parathyroid gland interaction

R. Tolouian, A. Baradaran
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Abstract

Lithium is a trace element that has been commonly used in treating bipolar affective disorder for years. Lithium therapy causes renal failure, several endocrine and metabolic abnormalities, such nephrogenic diabetes insipidus, thyroid abnormalities, and hypercalcemia. Early detection of lithium-related hypercalcemia and primary hyperparathyroidism will ameliorate patients’ situations. Besides, regular serum calcium and parathormone assessment in individuals on lithium therapy is strongly recommended.
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锂治疗与甲状旁腺的相互作用
锂是一种微量元素,多年来一直普遍用于治疗双相情感障碍。锂治疗可导致肾功能衰竭、多种内分泌和代谢异常,如肾源性尿崩症、甲状腺异常和高钙血症。早期发现锂相关的高钙血症和原发性甲状旁腺功能亢进将改善患者的情况。此外,强烈建议在接受锂治疗的个体中定期进行血清钙和甲状旁激素的评估。
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