The Effect of Chronic Swimming Exercise and Vitamin E Supplementation on Bone Element Metabolism in Epileptic Rats.

IF 0.9 4区农林科学 Q3 MATERIALS SCIENCE, PAPER & WOOD Nordic Pulp & Paper Research Journal Pub Date : 2023-12-07 eCollection Date: 2024-01-01 DOI:10.29399/npa.28495

Saltuk Buğra Baltacı, Erkut Tutkun, Mustafa Ayyıldız, Erdal Ağar, Gökhan Arslan, Rasim Moğulkoç, Abdülkerim Kasım Baltacı

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Abstract

Introduction: This study aimed to investigate the effects of chronic swimming exercise and vitamin E administration on elemental levels in the bone tissue of epileptic rats.

Methods: Forty-eight rats were divided into six groups: Control, Swimming, Swimming + vitamin E, Swimming + Epilepsy, Swimming + Epilepsy + vitamin E, and Epilepsy. Vitamin E was administered to the animals chronically by gavage at a dose of 500 mg/kg every other day for 3 months. Epileptiform activity was induced with penicillin in animals 24 hours after the last vitamin E intake. The exercise program consisted of daily 30-minute swimming sessions. At the end of the treatment period, the levels of calcium, chromium, copper, iron, magnesium, manganese, lead, and zinc (µg/gram tissue) in bone tissue samples were measured using an atomic emission device.

Results: The results showed that all epileptic groups had significantly lower bone chromium levels compared to the control groups (p<0.05). The epileptic, and epileptic swimming groups had the lowest levels of bone calcium, magnesium, and zinc (p<0.05). Vitamin E administration resulted in a significant increase in bone calcium, magnesium, and zinc levels in the epileptic swimming group with vitamin E compared to the epileptic and epileptic swimming groups. (p<0.05).

Conclusion: The findings of the study show that the administration of vitamin E improves calcium, magnesium, and zinc metabolism in the deteriorated bone tissue of the epileptic rat model.

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慢性游泳运动和维生素 E 补充剂对癫痫大鼠骨元素代谢的影响

引言本研究旨在探讨长期游泳运动和服用维生素 E 对癫痫大鼠骨组织中元素水平的影响：方法：将 48 只大鼠分为 6 组：对照组、游泳组、游泳 + 维生素 E 组、游泳 + 癫痫组、游泳 + 癫痫 + 维生素 E 组和癫痫组。给动物长期灌胃维生素 E，剂量为 500 毫克/千克，每隔一天灌胃一次，连续灌胃 3 个月。在最后一次摄入维生素 E 24 小时后，用青霉素诱导动物出现癫痫样活动。运动项目包括每天30分钟的游泳训练。治疗结束后，使用原子发射装置测量骨组织样本中钙、铬、铜、铁、镁、锰、铅和锌（微克/克组织）的含量：结果：结果显示，与对照组相比，所有癫痫组的骨铬含量都明显较低（p）：研究结果表明，服用维生素 E 可改善癫痫模型大鼠骨组织中钙、镁和锌的代谢。

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来源期刊

Nordic Pulp & Paper Research Journal 工程技术-材料科学：纸与木材

CiteScore

2.50

自引率

16.70%

发文量

审稿时长

1 months

期刊介绍： Nordic Pulp & Paper Research Journal (NPPRJ) is a peer-reviewed, international scientific journal covering to-date science and technology research in the areas of wood-based biomass: Pulp and paper: products and processes Wood constituents: characterization and nanotechnologies Bio-refining, recovery and energy issues Utilization of side-streams from pulping processes Novel fibre-based, sustainable and smart materials. The editors and the publisher are committed to high quality standards and rapid handling of the peer review and publication processes. Topics Cutting-edge topics such as, but not limited to, the following: Biorefining, energy issues Wood fibre characterization and nanotechnology Side-streams and new products from wood pulping processes Mechanical pulping Chemical pulping, recovery and bleaching Paper technology Paper chemistry and physics Coating Paper-ink-interactions Recycling Environmental issues.