Theranostics: A Boon in Cancer Diagnosis and Therapy

R. Jain, Hardik P. Raisoni, P. S. Pawar
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Abstract

Modern approaches in improvement of new nanomaterials have gained enormous attention due to various biomedical application, along with cancer theranostics. The characteristic physico-chemical feature of these materials, including their small size and wide-range surface-to-volume ratio provide potentiality for cancer theranostics that combine diagnosis , biosensing , imaging detection and immune therapy.Recent procurement for cancer immunotherapy have gained considerable attention in controlling the body’s immune system to fight against cancer.In this abstract , nanomedicine with inherent immunomodulatory properties presents interesting window(of opportunity) which can stimulate the function of immune cell. The goal is to cover broad range of information about the immunomodulation properties of nanomedicine in cancer theranostics i.e factors like pH, hypoxia, tumor angiogenesis, tumor extracellular matrix which have a huge role in the immunomodulation of nanomedicine and also strategies to enhance cancer theranostics applications. According to recent studies, cancer therapy can be potentially improved through nanoparticle based immunotherapy.
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治疗学:癌症诊断和治疗的福音
由于各种生物医学应用以及癌症治疗,新型纳米材料的现代改进方法得到了极大的关注。这些材料的物理化学特性,包括它们的小尺寸和大范围的表面体积比,为结合诊断、生物传感、成像检测和免疫治疗的癌症治疗提供了潜力。最近的癌症免疫治疗在控制人体免疫系统对抗癌症方面获得了相当大的关注。纳米药物具有固有的免疫调节特性,为刺激免疫细胞的功能提供了有趣的机会之窗。目标是涵盖纳米药物在癌症治疗中的免疫调节特性的广泛信息,即pH,缺氧,肿瘤血管生成,肿瘤细胞外基质等因素在纳米药物的免疫调节中起着巨大的作用,以及增强癌症治疗应用的策略。根据最近的研究,通过纳米粒子免疫疗法可以潜在地改善癌症治疗。
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