Retrotransposons and Complex Diseases: Is it Time for a Retrotransposon-Based âÂÂOmicsâ Profiling approach to Elucidate the Origins of Pathogenesis?

Dimitrios Noutsopoulos, A. Mitsioni
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Abstract

Volume 5 • Issue 2 • 1000223 Adv Tech Biol Med, an open access journal ISSN: 2379-1764 When Human Genome Project was completed, some unthinkable issues came to the fore. In contrast to the anticipations, the genic counterpart made up a mere ~2% of the genome. More surprisingly, it became evident the extent of the repetitive DNA, and we now know that it consists the most part of human genome [1,2].
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反转录转座子和复杂疾病:是时候用基于反转录转座子的âÂÂOmicsâÂÂ分析方法来阐明发病机制的起源了吗?
当人类基因组计划完成时,一些不可想象的问题出现了。与预期相反,对应基因只占基因组的2%左右。更令人惊讶的是,重复DNA的范围越来越明显,我们现在知道它构成了人类基因组的大部分[1,2]。
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