Epigenetic Status of Lebanese Dizygotic Twins

GABJ Pub Date : 2021-01-25 DOI:10.46325/gabj.v5i1.180
P. Romanos, J. Borjac
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Abstract

Lebanon is an eastern Mediterranean country with a small population of only 4 million (Abbas et al. 2020). It is characterized for its distinct human genetic, cultural, ethnic, and religious diversity (Haber et al. 2011). The average live twinning births rate in Lebanon is 18.9/1000 (Romanos & Borjac, 2018). Twins can be either monozygotic (MZ) or dizygotic (DZ). The difference between them is how they are formed during embryogenesis (Hoekstra et al. 2008). When a single sperm fertilizes a single egg, it splits then in two genetically identical twins (Xu et al. 2015). However, in fraternal twins case, separate eggs are fertilized by separate sperm to yield genetically different twins (Martino et al. 2013).
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黎巴嫩异卵双胞胎的表观遗传状况
黎巴嫩是一个东地中海国家,人口只有400万(Abbas et al. 2020)。它的特点是其独特的人类遗传、文化、种族和宗教多样性(Haber et al. 2011)。黎巴嫩的平均活双胞胎出生率为18.9/1000 (Romanos & Borjac, 2018)。双胞胎可以是同卵(MZ)或异卵(DZ)。它们之间的区别在于它们在胚胎发生过程中是如何形成的(Hoekstra et al. 2008)。当一个精子与一个卵子受精时,它会分裂成两个基因相同的双胞胎(Xu et al. 2015)。然而,在异卵双胞胎的情况下,不同的卵子由不同的精子受精,产生基因不同的双胞胎(Martino et al. 2013)。
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