Phytosomes: A Modernistic Approach for Novel Herbal Drug Delivery - Enhancing Bioavailability and Revealing Endless Frontier ofPhytopharmaceuticals

Sudhir Kumar, Ashish Baldi, D. Sharma
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引用次数: 19

Abstract

Phytopharmaceuticals are healing the world from millions and billions of years even though their clinical validation is questioned by virtue of their impediments like low lipid solubility, poor stability, large size moiety and needless metabolism in gut. Phytosome technology has emerged as committed and promising targeting novel drug delivery with improved efficacy, quality and target ability of active plant constituents. Novel herbal formulation techniques have assured the researchers to deliver the plant based secondary metabolites to their systemic targets. This review highlights the unique properties of phytophospholipid complex along with their application in the novel natural drug delivery. Various methods employed in phytosomal preparation and characterization along with the phytosomal advantages over conventional herbal extracts is described in the present review. The prospectus of phytosome technique can suggest new directions and endless frontier as novel drug regimen.
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磷脂体:一种新型草药药物传递的现代方法——提高生物利用度,揭示植物药的无尽前沿
植物药从数百万年到数十亿年一直在治愈世界,尽管它们的临床有效性受到质疑,因为它们的障碍,如低脂溶性,稳定性差,大尺寸部分和不必要的肠道代谢。光复体技术已成为一种有前途的新型靶向药物递送技术,它能提高植物活性成分的疗效、质量和靶向性。新的草药配方技术使研究人员能够将植物次生代谢物传递到其系统目标。本文综述了植物磷脂复合物的独特性质及其在新型天然药物传递中的应用。在目前的综述中描述了用于植体制备和表征的各种方法以及相对于传统草药提取物的植体优势。植物体技术作为一种新的药物治疗方案,具有广阔的应用前景。
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