5-n-Butyl-1-Cyclohexyl-2, 4, 6-Trioxoperhydropyrimidine (BCP)の抗体産生におよぼす影響

M. Kondo, K. Tsuchiya
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Abstract

The influence of 5-n-buthyl-1-cyclohexyl-2, 4, 6-trioxoperhydropyrimidine (BCP) on hemolysin formation against sheep red cells in mice was observed in comparison with that of cortisone. The drug was administered subcutaneously once daily for 4 days, starting from the 3rd day before (I), at the same time with (II) and on the 3rd day after (III) the intraperitoneal sensitization. While BCP gave no influence upon the antibody formation in (I), (II) and (III), cortisone suppressed markedly the hemolysin titer in (I) and (II), but showed no influence in (III).
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对5-n-Butyl-1-Cyclohexyl-2, 4,6 -Trioxoperhydropyrimidine (BCP)抗体产生的影响
与可的松比较,观察了5-正丁基-1-环己基- 2,4,6 -三氧过氢嘧啶(BCP)对小鼠羊红细胞溶血素形成的影响。于(I)前第3天、(II)同时、(III)后第3天腹腔致敏,每日皮下给药1次,连用4天。BCP对(I)、(II)和(III)的抗体形成没有影响,可的松明显抑制(I)和(II)的溶血素滴度,但对(III)没有影响。
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