{"title":"A new flavonoid glycoside from Trichilia emetica","authors":"A. Usman, V. Thoss, M. Nur-E-Alam","doi":"10.26655/JMCHEMSCI.2019.8.4","DOIUrl":null,"url":null,"abstract":"A new compound, catechin-3-O-α-L-rhamnopyranosyl (1→4) β-D-glucopyranoside was isolated from the ethylacetate soluble fraction of the aqueous extract of the whole seeds of Trichilia emetica (Family: Meliaceae). The structure of this compound was established on the basis of nuclear magnetic resonance (NMR), Infrared (IR) spectroscopy and ultraviolet-visible (UV-vis) spectrophotometry. The compound was also subjected to antimicrobial activity and brine shrimp lethality bioassay. The pure compound showed either no or reduced activity against microorganisms tested, it also showed no cytotoxicity.","PeriodicalId":16365,"journal":{"name":"Journal of Medicinal and Chemical Sciences","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2019-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"3","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Medicinal and Chemical Sciences","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.26655/JMCHEMSCI.2019.8.4","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 3
Abstract
A new compound, catechin-3-O-α-L-rhamnopyranosyl (1→4) β-D-glucopyranoside was isolated from the ethylacetate soluble fraction of the aqueous extract of the whole seeds of Trichilia emetica (Family: Meliaceae). The structure of this compound was established on the basis of nuclear magnetic resonance (NMR), Infrared (IR) spectroscopy and ultraviolet-visible (UV-vis) spectrophotometry. The compound was also subjected to antimicrobial activity and brine shrimp lethality bioassay. The pure compound showed either no or reduced activity against microorganisms tested, it also showed no cytotoxicity.
从吐毛毛菌(Trichilia emetica)全种子水提物的乙酸乙酯可溶性部分中分离得到一个新的化合物儿茶素-3- o -α-L-rhamnopyranosyl(1→4)β- d -葡萄糖吡喃苷。通过核磁共振(NMR)、红外(IR)和紫外-可见(UV-vis)分光光度法确定了该化合物的结构。并对该化合物进行了抗菌活性和盐水对虾致死性生物测定。纯化合物对微生物没有活性或活性降低，也没有细胞毒性。
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