Fungal infection in surgical pathology - Our institutional experience

Khushbu P. Shah, M. Patel
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引用次数: 1

Abstract

Background: Fungal infection has a worldwide prevalence and it affects almost all age groups and both the sexes. Due to neoteric treatment modalities nowadays, people are enjoying longevity of life. However, on the other hand, immune status is compromised that has resulted in increased prevalence of fungal infection in society. Fungi reported by surgical pathologist, either incidentally or in clinically suspicious cases, greatly improve morbidity and outcome of the patients. Objective: The objective of this study is to study the prevalence of fungal infection in surgical pathology tissue and frequency and spectrum-based analysis in relation to age, gender, and systemic involvement. Materials and Methods: Ethically approved retrospective observational secondary data analysis is done based on histomorphological and cytomorphological evaluation of 17 fungal cases diagnosed at the Department of Pathology, New Civil Hospital, Surat, from January 2015 to January 2017. Results: Out of 17 cases, most common fungus seen was Candida albicans mainly affecting gastrointestinal tract. Common age group affected was 41–60 years and few rare fungi, i.e., mucormycosis and tinea corporis were also reported. Conclusion: Distribution of fungi in tissue section in relation to frequency, age, sex, various organs, and its correlation with clinical symptoms is analyzed in our study and results are found to be yielding that provided outlook in the prevalence of infectious agent.
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外科病理中的真菌感染-我们的机构经验
背景:真菌感染在世界范围内流行,它影响几乎所有年龄组和两性。由于现代的治疗方式,人们正在享受长寿。然而,另一方面,免疫状态受到损害,导致社会中真菌感染的患病率增加。外科病理学家报告的真菌,无论是偶然的还是临床可疑的病例,都大大提高了患者的发病率和预后。目的:本研究的目的是研究外科病理组织中真菌感染的患病率,以及与年龄、性别和全身累及相关的频率和频谱分析。材料与方法:对2015年1月至2017年1月在苏拉特新民建医院病理科诊断的17例真菌病例进行组织形态学和细胞形态学评价,进行回顾性观察性二次资料分析,经伦理批准。结果:17例中以白色念珠菌为主,主要累及胃肠道。常见年龄组为41 ~ 60岁,罕见真菌如毛霉病和体癣也有报道。结论:本研究分析了真菌在组织切片中的分布与频率、年龄、性别、各器官的关系及其与临床症状的相关性,为感染性病原体的流行提供了前景。
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