Characterisation of Microscopic Changes in Macroscopically Unaffected Peritoneum in Women with and without Endometriosis

Mira Luhmann, V. Chiantera, J. Sehouli, S. Mechsner
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Abstract

Study question: Is there a difference in the occurrence of occult microscopic endometriotic lesions in normal peritoneum between women with and without endometriosis and if so are there other differences in the structure of the peritoneum between these groups? 1986. then has more research on the topic but without finding any conclusions about the clinical significance. Therefore, OME could be a physiological phenomenon that occurs in women with and without could be early of real EM lesions. CD10, and Anti-Smooth Muscle Cell Actin (ASMA). Results: OME lesions were found in five of the 86 patients (5, 81%). One of these lesions was found in a woman without EM which is 4, 5% of the control group. In the group of women with EM, there were four patients with OME lesions which is 6, 3% of the cohort, so there was no statistically significant difference between these groups. Besides the OME lesions, there were immune cells found in the tissue of 12 women with EM (18, 8% of the EM cohort) but none in the control group. These findings did not correlate with the OME lesions.
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有或没有子宫内膜异位症的女性未受宏观影响的腹膜的显微变化特征
研究问题:在有和没有子宫内膜异位症的女性中,正常腹膜中隐性显微镜下子宫内膜异位症病变的发生率是否有差异?如果有,这两组之间的腹膜结构是否有其他差异?1986. 然后对这个话题进行了更多的研究,但没有发现任何关于临床意义的结论。因此,OME可能是一种生理现象,发生在有或没有真正EM病变的女性中可能是早期的。CD10和抗平滑肌细胞肌动蛋白。结果:86例患者中有5例出现OME病变(5.81%)。其中一个病变是在没有EM的女性身上发现的占对照组的4.5%。在患有EM的女性组中,有4名患者患有OME病变,占队列的6.3%,因此这些组之间没有统计学上的显著差异。除了OME病变外,在12名EM女性(EM队列的18.8%)的组织中发现了免疫细胞,但在对照组中没有。这些发现与OME病变无关。
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