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“A Spirit Encroachment”: Hysterical Possession, Case Study from Kerala "精神侵袭":癔症附身,喀拉拉邦的案例研究
Pub Date : 2024-07-15 DOI: 10.31038/awhc.2024724
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引用次数: 0
The Evolving Landscape of Gender and Happiness: A Commentary “Does Reversal of the Educational Gender Gap Affect Men’s Happiness: Evidence from China” 性别与幸福的演变:评论 "教育性别差距的逆转会影响男性的幸福吗?来自中国的证据
Pub Date : 2024-06-10 DOI: 10.31038/awhc.2024721
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引用次数: 0
Update on the Management of Status Asthmaticus Gravidus and Acute Severe Asthma during Pregnancy 妊娠期哮喘和急性重症哮喘的最新管理方法
Pub Date : 2024-03-25 DOI: 10.31038/awhc.2024712
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引用次数: 0
Women-Led Climate Change Solution Satellites: A Key Contributor to Social and Economic Empowerment of Women in Uganda 妇女主导的气候变化解决方案卫星:为乌干达妇女的社会和经济赋权做出重要贡献
Pub Date : 2024-01-22 DOI: 10.31038/awhc.2024711
Comfort Hajra, Mukasa, Arnold Tigaiza, Rosemary Atieno, Elaine McCarty
Abstract
摘要
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引用次数: 0
Impact of the COVID-19 Pandemic on Breast Incidence and Stage during the COVID-19 Pandemic in the Netherlands, and a Comparison with Other Countries COVID-19 大流行对荷兰 COVID-19 大流行期间乳腺癌发病率和阶段的影响,以及与其他国家的比较
Pub Date : 2023-12-11 DOI: 10.31038/awhc.2023643
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引用次数: 0
Do Late, Low-level Interventions Improve Chronic War Trauma Related Symptoms? 后期低水平干预能否改善与战争创伤相关的慢性症状?
Pub Date : 2023-11-17 DOI: 10.31038/awhc.2023642
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引用次数: 0
A Case Report of Dicephalus Parapagus Conjoint Twins: Declined Caesarean Section for Obstructed Labour; Fetal Death in Utero and Successful Vaginal Delivery 双头准双生双胞胎难产拒绝剖腹产1例子宫内胎儿死亡和阴道分娩成功
Pub Date : 2023-07-18 DOI: 10.31038/awhc.2023632
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引用次数: 0
Differences in the Pandemic? Qualitative Study of Gender as a Social Determinant 大流行的差异?性别作为社会决定因素的定性研究
Pub Date : 2023-07-11 DOI: 10.31038/awhc.2023631
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引用次数: 0
Faking Orgasm: Interviews with College Women about How, When, and Why They Pretend to Experience Orgasm 《假装高潮:采访大学女生如何、何时、为何假装高潮》
Pub Date : 2023-06-23 DOI: 10.31038/awhc.2023623
Lanie Howes, Sandra L Caron, Cynthia Erdley
a
一个
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引用次数: 0
Polynucleotides/Sodium Hyaluronate Ovules for Postmenopausal Vulvovaginal Atrophy and Other Vaginal Environment Disorders 多核苷酸/透明质酸钠用于绝经后外阴阴道萎缩和其他阴道环境疾病
Pub Date : 2023-06-23 DOI: 10.31038/awhc.2023624
Michela Angelucci, Anna Angela Criscuolo, Alessandra Lusi
Introduction: Vulvovaginal atrophy, as the most troublesome symptom complex within the more comprehensive clinical picture of Genitourinary Syndrome of Menopause, severely impacts the postmenopausal women’s quality of life, their self-respect as still attractive women, and possibly the women’s couple relationship. The same may happen at a younger age, with vaginal dryness as an occasional side effect of estro-progestin oral contraceptives, hormone-releasing vaginal rings, and other disorders leading to a deranged vaginal environment. Based on a sound rationale, a new medical device based on natural-origin polynucleotides and sodium hyaluronate formulated as vaginal ovuli may help over the long term with those frequent hassles of middle-aged and younger women. Methods: Design: a survey investigation based on a questionnaire compiled by three investigators familiar with the new vaginal ovuli medical device in their everyday office practice. The investigators completed the survey based on outcomes in 45 ambulatory adult women (≥18 years old). All women had freely consulted the investigators to seek relief from vulvovaginal atrophy symptoms and vaginal dryness as a contraceptive side effect. The minimal inclusion and exclusion criteria helped simulate a real-world office situation. The survey followed a treatment cycle with a Class-III CE-marked medical device (Ovuli PNHA, Mastelli S.r.l., Sanremo, Italy—vaginal ovules with 0.25% polynucleotides, 0.25% non-cross-linked sodium hyaluronate, and 3% polycarbophil as functional ingredients). After the end of the self-administration cycle (one ovule intravaginally per day for two to four weeks), the survey’s goal was to assess the impressions of investigators and their patients about the safety and efficacy (symptom relief, restoration of a healthy vaginal environment) of the medical device in all conditions of vulvovaginal atrophy/vaginal dryness and dystrophic lesions/vaginal environment disorders. The device establishes a protective, moisturizing, and pH-controlled lubricating film onto the cervix and vaginal mucosa and promotes its physiological regenerative and reparative mechanisms. Assessment tools at baseline and after the end of the treatment cycle: Vaginal Health Index score (validated investigator-assessed five-item scale, with scores ranging from 5 to 25 and <15 as dryness and atrophy score threshold); subjective VVA symptom severity (vaginal dryness, vulvovaginal irritation/itching, vulvovaginal soreness, dyspareunia) assessed by the patients with the support of a series of five-point VAS scales (0=absent, 1=mild, 2=moderate, 3=severe, 4 = very severe). Results: The surveyed investigators stated that the mean total VHI score significantly improved over the follow-up period, from 2.5 ± 0.94 to 3.6 ± 0.85 (p <0.001 vs. baseline). The mucosal thickness and integrity, showing severe or very severe atrophy in 13 surveyed women at baseline, presented no more than some mild atrophy in 91.1% of women,
外阴阴道萎缩是绝经期泌尿生殖系统综合征临床表现中最麻烦的症状,严重影响绝经后妇女的生活质量,影响她们作为有吸引力女性的自尊,甚至可能影响妇女的夫妻关系。同样的情况也可能发生在年轻时,阴道干涩是雌激素-黄体酮口服避孕药、释放激素的阴道环和其他导致阴道环境紊乱的疾病的偶然副作用。基于一个合理的原理,一种基于天然多核苷酸和透明质酸钠的新型医疗设备可能会长期帮助中年和年轻女性解决那些经常出现的麻烦。方法:设计:由3名熟悉新型阴道卵泡医疗器械的调查人员在日常办公实践中编制问卷进行调查。研究人员根据45名成年女性(≥18岁)的结果完成了调查。所有妇女都自由地咨询了调查人员,以寻求缓解外阴阴道萎缩症状和阴道干燥作为避孕副作用。最小的包含和排除标准有助于模拟现实世界的办公室情况。该调查遵循了一个iii类ce标记医疗器械的治疗周期(Ovuli PNHA, Mastelli S.r.l, Sanremo,意大利-阴道胚珠,含0.25%多核苷酸,0.25%非交联透明质酸钠和3%多酚作为功能成分)。在自我给药周期结束后(每天阴道内一个胚囊,持续两到四周),调查的目标是评估调查人员及其患者对医疗器械在外阴阴道萎缩/阴道干燥和营养不良病变/阴道环境紊乱的所有情况下的安全性和有效性(症状缓解,恢复健康的阴道环境)的印象。本装置在宫颈和阴道粘膜上建立起一层保护性、保湿性和ph控制的润滑膜,促进其生理性再生和修复机制。基线和治疗周期结束后的评估工具:阴道健康指数评分(经验证的研究者评估的五项量表,评分范围从5到25,<15为干燥和萎缩评分阈值);主观VVA症状严重程度(阴道干燥,外阴阴道刺激/瘙痒,外阴阴道疼痛,性交困难)由患者在一系列五点VAS量表(0=无,1=轻度,2=中度,3=严重,4 =非常严重)的支持下评估。结果:调查人员表示,在随访期间,平均总VHI评分显著提高,从2.5±0.94到3.6±0.85(与基线相比p <0.001)。13名受访女性的粘膜厚度和完整性在基线时表现为严重或非常严重的萎缩,91.1%的女性表现为轻度萎缩,35.6%的受访女性恢复到完全恢复和完整。阴道干燥也从基线显著下降,79%的队列妇女改善到轻度萎缩或症状消除,21%恢复到恢复和完整。关于主观症状缓解,被调查妇女报告平均总VAS评分(累计计算阴道瘙痒、阴道灼烧、阴道疼痛、性交时疼痛/不适和阴道干燥)从3.5±0.70降低到2.1±0.73(与基线相比p <0.001)。偶有轻度局部疼痛和刺激,无临床意义,且迅速短暂。结论:多核苷酸和透明质酸钠作为阴道卵泡的新配方有效地抵消了绝经后妇女由于外阴阴道萎缩引起的症状复合物,包括雌激素治疗禁忌症和阴道干燥作为避孕副作用的年轻妇女。该研究证实,PNs与透明质酸协同作用,保留了其创新潜力,作为外阴阴道组织生理再生和修复过程的非药物激活剂。该研究还证实了这种新型装置的安全性和女性对治疗的依从性。
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引用次数: 0
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Archives of women health and care
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