Usefulness of colchicine for Covid-19 myopericarditis in athletes. A case report and review of the literature

A. Deligiannis, Efthymia Dervisopoulou, E. Kouidi
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Abstract

Cardiac injuries, specifically acute myocarditis, are a common complication of COVID-19. Recent studies in the literature have supported the beneficial and safe results of colchicine administration in the general population in cases of COVID-19 infection, especially in cases of myocardial injuries. However, the frequency of occurrence in athletes, its treatment, and management of these individuals concerning the return to competitive sports have not yet been clarified. The present case description is a novelty in that it refers to the onset of a mild form of acute myopericarditis secondary to COVID-19 infection in an athlete that was successfully treated as an outpatient with only colchicine. A 45-year-old marathon runner with no underlying health problems showed clinical symptoms of acute pericarditis and mild febrile infection. The biochemical tests were characterized by an increase in the level of troponin. MRI established the diagnosis of mild myopericarditis. In addition, he has been tested positive for COVID-19 by molecular/PCR test. The patient was treated with colchicine alone for three months. After that time, all the clinical and laboratory findings of myopericarditis were subsided. Six months after the onset of the disease, the athlete returned to full competitive action.
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秋水仙碱对运动员Covid-19心包炎的疗效。病例报告及文献回顾
心脏损伤,特别是急性心肌炎,是COVID-19的常见并发症。最近的文献研究支持了秋水仙碱在普通人群中对COVID-19感染的有益和安全的结果,特别是在心肌损伤的情况下。然而,在运动员中发生的频率,其治疗和管理这些个人有关重返竞技体育尚未明确。本病例描述的新颖之处在于,它涉及一名仅使用秋水仙碱成功治疗门诊的运动员继发于COVID-19感染的轻度急性心包炎。45岁马拉松运动员,无潜在健康问题,临床表现为急性心包炎和轻度发热感染。生化试验的特点是肌钙蛋白水平升高。MRI诊断为轻度心包炎。此外,他的分子/PCR检测结果呈阳性。患者单用秋水仙碱治疗3个月。此后,所有心包炎的临床和实验室检查结果均消退。发病6个月后,这位运动员恢复了全面的竞技活动。
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