Liquid Herbal Mixed of Indian Borage Extract and Tamarind Flesh As Anti-diabetes

Abstract

Please cite this article as: Utari et al., Liquid Herbal Mixed of Indian Borage Extract and Tamarind Flesh As Anti-diabetes. American Journal of PharmTech Research 2019. Liquid Herbal Mixed of Indian Borage Extract and Tamarind Flesh As Anti-diabetes Utari dan Erni Rustiani Pharmacy Study Program, Mathematics & Sciences Faculty, Pakuan University, Bogor ABSTRACT Indian borage leaves (Coleus amboinicus) at dose of 620mg/KgBB and tamarind (Tamarindus indica) at dose of 300mg/KgBB effectively decrease glucose contain in blood with work mechanism by reducing oxidative stress in body. Flavonoid contain in these plants was thought to play role as anti-diabetes. Because of the efficacy similarity of these plants, so the combination of Indian borage and tamarind extract was made in liquid herbal dosage form. The liquid herbal in this research were intended to oral use, so they can be given additional flavoring, sweetener, or watersoluble dyes to improve dosage quality. Liquid herbal dosage were made in 4 formulas based on different types of sweeteners, the test result showed that liquid herbal with palm sugar sweetener was the most preferred by panellists. Selected formulas from the test of preference was tested for quality testing include : stabilization test at three different temperatures over a period of 8 weeks with parameters pH measuring, viscosity, specific gravity, organoleptic, determination of flavonoid content and testing of microbial contamination. Stability test result showed a change in the quality and decrease in flavonoid levels in liquid herbals dosage every week. Based on data on the decrease in flavonoid contain in stability test, the prediction of the shelf life of liquid herbals dosage was obtained for 8 week at room temperature.