Innovative Observation of MDA-MB-231 Cell Vitality in Mice Upon 266-nm Laser Irradiation

Ray-Ling Hsiao, Ying-chun Chen, Chiang-Yun Chen, Yu-Wei Lin, Chung-Yi Wu
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Abstract

In this innovative experiment, MDA-MB-231 cells were irradiated with a 266-nm laser for 5s, and then injected into NOD/SCID mice. The survival rate of the experimental mice was significantly reduced compared to that of the control mice (p=0.029), which also indicated the vitality of the experimental cells in vivo. The enhancement effect of a 266-nm laser on cells in xenotransplantation after 5 s of exposure was studied for the first time in this study. The findings of this study provide potential for future live cell therapies.
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266nm激光照射小鼠MDA-MB-231细胞活力的创新观察
本实验采用266 nm激光照射MDA-MB-231细胞5s,然后注射到NOD/SCID小鼠体内。与对照组相比,实验小鼠的存活率明显降低(p=0.029),这也说明了实验细胞在体内的活力。本研究首次研究了266 nm激光照射5 s后对异种移植细胞的增强作用。这项研究的发现为未来的活细胞治疗提供了可能。
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