LB1 Is higher perceived social support related to greater participation in cardiovascular disease (CVD) risk reducing behaviours for people with severe mental illnesses (SMI)?

A. Burton, K. Walters, D. Osborn
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Abstract

Background The mortality gap for people with SMI from CVD is increasing. Studies have found a positive relationship between perceived social support and CVD outcomes in the general population; however there has been less research in people with SMI. Social support may influence CVD outcomes through encouraging participation in healthy lifestyle activities. Aims To assess whether higher social support as measured by the Medical Outcomes Study–Social Support Survey (MOS-SSS) is associated with greater attendance at primary care intervention appointments. Secondary outcomes included:adherence to CVD medications (Morisky Medication Adherence Scale (MMAS)),physical activity (International Physical Activity Questionnaire (IPAQ)),diet (Dietary Instrument for Nutrition Education (DINE))alcohol consumption (Alcohol Use Disorders Identification Test (AUDIT)),self–reported smoking behaviour Methods Longitudinal and cross sectional studies involving 326 patients with SMI and raised CVD risk factors. Participants were recruited from 76 GP practices in England to a clinical trial assessing the effectiveness of a behavioural intervention for reducing CVD risk in people with SMI against routine GP practice care. Secondary data analysis used random effects linear regression models for continuous outcomes, logistic regression for binary outcomes, and Poisson/negative binomial regression models for count outcomes. Results A weak association between social support and attendance at primary care intervention appointments was identified. As social support scores increased by one point, the appointment attendance rate increased by 0.5% (IRR=1.0053; 1.0001–1.0105, p=0.05). When sex, age, ethnicity, diagnosis and deprivation were entered into the model, this association decreased to 0.3% and was no longer significant (IRR=1.0032; 0.9980–1.0085, p=0.23). A strong association between social support and CVD medication adherence was identified. The odds of being in the moderate/high adherence group compared to the low adherence group increased by 3.9% with a one point increase on the MOS-SSS (OR=1.0385; 1.0176 to 1.0598, p<0.001). This association remained significant when sex, age, ethnicity, diagnosis and deprivation were included in the model (OR=1.0390; 1.0133–1.0648, p=0.003). No significant associations were identified between social support and physical activity, diet, alcohol or smoking. Conclusions Social support may be an important facilitator for attendance at appointments and adherence to CVD medications; however no association was found between social support and lifestyle behaviours. Harnessing positive social relationships in the delivery of interventions for reducing CVD risk in this population should be considered as a strategy for encouraging uptake.
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对于重度精神疾病(SMI)患者,更高的感知社会支持是否与更多参与心血管疾病(CVD)风险降低行为有关?
背景:心血管疾病致重度精神分裂症患者的死亡率差距正在扩大。研究发现,在一般人群中,感知到的社会支持与心血管疾病结局之间存在正相关关系;然而,对重度精神分裂症患者的研究却很少。社会支持可以通过鼓励参与健康的生活方式活动来影响心血管疾病的结局。目的评估由医疗结果研究-社会支持调查(MOS-SSS)测量的较高的社会支持是否与较高的初级保健干预预约出勤率相关。次要结局包括:对心血管疾病药物的依从性(莫里斯基药物依从性量表(MMAS))、体育活动(国际体育活动问卷(IPAQ))、饮食(营养教育饮食工具(DINE))、饮酒(酒精使用障碍识别测试(AUDIT))、自我报告的吸烟行为。方法纵向和横断面研究涉及326例重度精神障碍患者和心血管疾病风险因素升高的患者。参与者从英格兰的76家全科医生诊所招募,参加一项临床试验,评估行为干预对降低重度精神障碍患者心血管疾病风险的有效性,而不是常规全科医生护理。辅助数据分析使用随机效应线性回归模型进行连续结果分析,使用逻辑回归模型进行二元结果分析,使用泊松/负二项回归模型进行计数结果分析。结果社会支持与参加初级保健干预预约之间存在弱关联。社会支持分数每增加1分,预约出勤率增加0.5% (IRR=1.0053;1.0001 - -1.0105, p = 0.05)。当将性别、年龄、种族、诊断和剥夺纳入模型时,这种关联降至0.3%,不再显著(IRR=1.0032;0.9980 - -1.0085, p = 0.23)。社会支持与心血管疾病药物依从性之间存在强烈关联。与低依从性组相比,中/高依从性组的几率增加了3.9%,MOS-SSS增加了1点(OR=1.0385;1.0176 ~ 1.0598, p<0.001)。当模型中包括性别、年龄、种族、诊断和剥夺时,这种关联仍然显著(OR=1.0390;1.0133 - -1.0648, p = 0.003)。没有发现社会支持与体育活动、饮食、饮酒或吸烟之间存在显著关联。结论社会支持可能是心血管疾病患者按时就诊和依从性药物治疗的重要促进因素;然而,没有发现社会支持和生活方式行为之间的联系。在这一人群中,利用积极的社会关系提供降低心血管疾病风险的干预措施,应被视为一种鼓励采用的策略。
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