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Early adulthood socioeconomic trajectories contribute to inequalities in adult diet quality, independent of childhood and adulthood socioeconomic position 成年早期的社会经济轨迹导致了成年饮食质量的不平等,与童年和成年期的社会经济地位无关
Pub Date : 2024-09-18 DOI: 10.1136/jech-2024-222472
Yinhua Tao, Jane Maddock, Laura Howe, Eleanor M Winpenny
Background Diet is an important risk factor for cardiovascular disease and shows well-established socioeconomic patterning among adults. However, less clear is how socioeconomic inequalities in diet develop across the life course. This study assessed the associations of early adulthood socioeconomic trajectories (SETs) with adult diet quality, adjusting for childhood socioeconomic position (SEP) and testing for mediation by adulthood SEP. Methods Participants from the 1970 British Cohort Study with socioeconomic data in early adulthood were included (n=12 434). Diet quality at age 46 years, evaluated using the Mediterranean diet pyramid, was regressed on six previously identified classes of early adulthood SETs between ages 16 and 24 years including a continued education class, four occupation-defined classes and an economically inactive class. Causal mediation analyses tested the mediation of the association via household income and neighbourhood deprivation at age 46 years separately. Models were adjusted for sex, childhood SEP, adolescent diet quality and adolescent health. Results The continued education class showed the best diet quality at age 46 years while little difference in diet quality was found among the remaining SET classes. The association between the continued education class and adult diet quality was independent of parental SEP in childhood and was largely not mediated by household income or neighbourhood deprivation (0.7% and 3.7% of the total effect mediated, respectively) in mid-adulthood. Conclusions Early adulthood SETs independently contribute to adult diet quality with continuing education associated with better adherence to the Mediterranean diet. Early adulthood therefore represents a sensitive period for intervention to alleviate dietary inequalities in later life. Data are available in a public, open access repository. Data are available in a public, open access repository. The data underlying this article are freely available to bona fide researchers via the UK Data Service ().
背景 饮食是心血管疾病的重要风险因素,在成年人中表现出成熟的社会经济模式。然而,在整个生命过程中,饮食中的社会经济不平等是如何形成的却不太清楚。本研究评估了成年早期社会经济轨迹(SETs)与成人饮食质量的关系,调整了儿童时期的社会经济地位(SEP),并检验了成年期社会经济地位对饮食质量的调节作用。方法 将 1970 年英国队列研究(British Cohort Study)中有成年早期社会经济数据的参与者(n=12 434)纳入研究。采用地中海饮食金字塔对 46 岁时的饮食质量进行评估,并将其与之前确定的 16-24 岁成年早期社会经济地位的六个等级(包括一个继续教育等级、四个职业定义等级和一个不从事经济活动等级)进行回归。因果中介分析分别测试了 46 岁时家庭收入和邻里贫困对这一关联的中介作用。对模型进行了性别、童年 SEP、青少年饮食质量和青少年健康调整。结果 46 岁时,继续教育班级的饮食质量最好,而其余 SET 班级的饮食质量差别不大。继续教育等级与成人饮食质量之间的关系与儿童时期父母的 SEP 无关,而且在成年中期基本上不受家庭收入或邻里贫困的影响(分别占总影响的 0.7% 和 3.7%)。结论 成年早期的 SETs 对成年后的饮食质量有独立的影响,持续教育与更好地坚持地中海饮食有关。因此,成年早期是采取干预措施以减轻日后饮食不平等的敏感时期。数据可在公开、开放的资源库中获取。数据可在公开、开放的资源库中获取。本文所依据的数据可通过英国数据服务()免费提供给真正的研究人员。
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引用次数: 0
Education-related inequalities in disability during the last years of life: a full population register-based study 生命最后几年与教育有关的残疾不平等:基于全人口登记的研究
Pub Date : 2024-09-11 DOI: 10.1136/jech-2024-222669
Erwin Stolz, Moritz Oberndorfer, Wolfgang Freidl
Background Little is known about education-related inequalities in late-life disability. Here, we use individual-level register data on the receipt of the Austrian long-term care allowance (ALTCA) to assess education-related inequalities in the duration of late-life disability. Methods In this retrospective mortality follow-back study, we analyse receipt of ALTCA, a universal cash benefit based on physician-assessed disability in activities of daily living, during the last 5 years of life among all decedents aged 65 years and over from 2020 in Austria (n=76 772). Results The higher the level of education, the shorter the period for which ALTCA was received. Over the last 5 years of life, those with the primary/lower secondary education received ALTCA for 47% or 10 months (men), respectively, 38% or 12 months (women) longer than those with tertiary education. Education-related inequalities decreased with time to death and age at death. Conclusion We found education-related inequalities in the duration of late-life disability, that is, higher education was associated with a prolonged ability to live independently during the last years of life. Inequalities in disability decreased with time to death and age at death, pointing to a gradual levelling due to mortality-related declines as well as selective mortality.
背景 对晚年残疾中与教育相关的不平等现象知之甚少。在此,我们利用有关领取奥地利长期护理津贴(ALTCA)的个人层面登记数据来评估晚年残疾持续时间中与教育相关的不平等现象。方法 在这项回顾性死亡率跟踪研究中,我们分析了自 2020 年以来奥地利所有 65 岁及以上死者(n=76 772)在生命最后 5 年中领取 ALTCA 的情况。结果 受教育程度越高,领取 ALTCA 的时间越短。在生命的最后 5 年中,与受过高等教育的人相比,受过小学/初中教育的人接受 ALTCA 的时间分别长 47% 或 10 个月(男性),38% 或 12 个月(女性)。与教育相关的不平等随着死亡时间和死亡年龄的增加而减少。结论 我们发现在晚年残疾的持续时间上存在与教育相关的不平等,也就是说,教育程度越高,晚年独立生活的时间越长。残疾方面的不平等随着死亡时间和死亡年龄的增加而减少,这表明由于死亡率的下降以及选择性死亡,残疾方面的不平等逐渐趋于平稳。
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引用次数: 0
Impact of increasing workforce racial diversity on black-white disparities in cardiovascular disease mortality 增加劳动力种族多样性对心血管疾病死亡率黑白差异的影响
Pub Date : 2024-09-09 DOI: 10.1136/jech-2024-222094
Hilary L Colbeth, Corinne A Riddell, Marilyn Thomas, Mahasin Mujahid, Ellen A Eisen
Background Structural racism’s influence on workforce policies and practices presents possible upstream targets for assessing and reducing racial health disparities. This study is the first to examine workforce racial diversity in association with racial disparities in cardiovascular disease (CVD) outcomes. Methods This retrospective cohort study of 39 693 hourly autoworkers from three Michigan automobile plants, includes 75 years of follow-up (1941–2015). Workforce racial diversity (per cent black autoworkers) was a plant and year level variable. Annual exposure was cumulated over each individual’s working life and divided by time since hire. This time-varying measure was categorised into low, moderate and high. We estimated age-standardised rates of CVD and Cox proportional HRs by race. Results CVD mortality per 100 000 person-years decreased among autoworkers over the study period; however, black workers’ rates remained higher than white workers. Among black workers, we observed a strong protective association between greater workforce racial diversity and CVD mortality. For example, at the Detroit plant, the HR for moderate exposure to racial diversity was 0.94 (0.83, 1.08) and dropped to 0.78 (0.67, 0.90) at the highest level. Among white workers, results were mixed by plant, with protective effects in plants where less than 20% of workers were black and null results where black workers became the majority. Conclusion Our findings provide evidence that workplace racial diversity may reduce CVD mortality risk among black workers. Workplace practices encouraging diverse hiring and retention have potential to improve all workers’ health; particularly the socially racialised groups in that workforce. Data are available upon reasonable request. Data are available upon reasonable request, with limitations to preserve the autonomy and the rights of the individual participants.
背景结构性种族主义对劳动力政策和实践的影响为评估和减少种族健康差异提供了可能的上游目标。本研究首次探讨了劳动力种族多样性与心血管疾病(CVD)结果种族差异的关系。方法 这项回顾性队列研究对密歇根州三家汽车厂的 39 693 名小时工进行了长达 75 年(1941-2015 年)的跟踪调查。劳动力种族多样性(黑人汽车工人百分比)是一个工厂和年份级别的变量。年暴露量是每个人工作年限的累积值,除以受雇以来的时间。这种随时间变化的测量值分为低、中和高。我们按种族估算了心血管疾病的年龄标准化比率和 Cox 比例 HRs。结果 在研究期间,汽车工人每 10 万人年的心血管疾病死亡率有所下降;但是,黑人工人的心血管疾病死亡率仍然高于白人工人。在黑人工人中,我们观察到劳动力种族多样性与心血管疾病死亡率之间存在很强的保护性联系。例如,在底特律工厂,种族多样性中度暴露的 HR 为 0.94 (0.83, 1.08),最高水平时降至 0.78 (0.67, 0.90)。在白人工人中,各工厂的结果不一,黑人工人比例低于 20% 的工厂具有保护作用,而黑人工人占多数的工厂则没有保护作用。结论 我们的研究结果提供了工作场所种族多样性可降低黑人工人心血管疾病死亡风险的证据。工作场所鼓励多元化招聘和留用的做法有可能改善所有工人的健康状况,尤其是劳动力中的社会种族群体。如有合理要求,可提供数据。数据可在合理要求下提供,但有限制条件,以维护参与者的自主权和个人权利。
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引用次数: 0
Gender-specific aspects of socialisation and risk of cardiovascular disease among community-dwelling older adults: a prospective cohort study using machine learning algorithms and a conventional method 社会化与社区老年人心血管疾病风险的性别差异:利用机器学习算法和传统方法进行的前瞻性队列研究
Pub Date : 2024-06-05 DOI: 10.1136/jech-2023-221860
Achamyeleh Birhanu Teshale, Htet Lin Htun, Alice J. Owen, Joanne Ryan, JR Baker, Mor Vered, Christopher M Reid, Robyn L. Woods, Michael Berk, Andrew Tonkin, Johannes T Neumann, Monique F Kilkenny, Aung Zaw Zaw Phyo, Mark R Nelson, Nigel Stocks, Carlene Britt, Rosanne Freak-Poli
Background Gender influences cardiovascular disease (CVD) through norms, social relations, roles and behaviours. This study identified gender-specific aspects of socialisation associated with CVD. Methods A longitudinal study was conducted, involving 9936 (5,231 women and 4705 men) initially healthy, community-dwelling Australians aged 70 years or more from the ASPirin in Reducing Events in the Elderly (ASPREE) study and ASPREE Longitudinal Study of Older Persons, with a median follow-up time of 6.4 years. Variable categorisation, variable selection (using machine learning (ML) models; Elastic Net and extreme gradient boosting) and Cox-regression were employed separately by binary gender to identity socialisation factors (n=25 considered) associated with CVD. Results Different socialisation factors were identified using the ML models. In the Cox model, for both genders, being married/partnered was associated with a reduced risk of CVD (men: HR 0.76, 95% CI 0.60 to 0.96; women: HR 0.67, 95% CI 0.58 to 0.95). For men, having 3–8 relatives they felt close to and could call on for help (HR 0.76, 95% CI 0.58 to 0.99; reference <3 relatives), having 3–8 relatives they felt at ease talking with about private matters (HR 0.70, 95% CI 0.55 to 0.90; reference <3 relatives) or playing games such as chess or cards (HR 0.82, 95% CI 0.67 to 1.00) was associated with reduced risk of CVD. For women, living with others (HR 0.71, 95% CI 0.55 to 0.91) or having ≥3 friends they felt at ease talking with about private matters (HR 0.74, 95% CI 0.58 to 0.95; reference <3 friends) was associated with a lower risk of CVD. Conclusions This study demonstrates the need to prioritise gender-specific social factors to improve cardiovascular health in older adults. Data may be obtained from a third party and are not publicly available. The ASPREE and ALSOP are not publicly available since they are ongoing. However, they are available to partnering and external researchers for projects of appropriate scientific merit and expressions of interest to analyse data from these datasets are co-ordinated through the ASPREE Access Management Site (AMS) ().
背景 性别通过规范、社会关系、角色和行为影响心血管疾病(CVD)。本研究确定了与心血管疾病相关的社会化的性别特异性方面。方法 进行了一项纵向研究,涉及9936名(5231名女性和4705名男性)最初健康的、居住在社区的70岁或70岁以上的澳大利亚人,他们来自 "ASPirin in Reducing Events in the Elderly (ASPREE) "研究和 "ASPREE Longitudinal Study of Older Persons "研究,中位随访时间为6.4年。按照二元性别分别采用变量分类、变量选择(使用机器学习(ML)模型;弹性网和极度梯度提升)和 Cox 回归来识别与心血管疾病相关的社会化因素(25 个考虑因素)。结果 使用 ML 模型确定了不同的社会化因素。在 Cox 模型中,男女已婚/有伴侣与心血管疾病风险降低有关(男性:HR 0.76,95% CI 0.60 至 0.96;女性:HR 0.67,95% CI 0.58 至 0.95)。对于男性而言,有 3-8 名亲属与他们关系密切并可向他们求助(HR 0.76,95% CI 0.58 至 0.99;参考值)。
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引用次数: 0
Poverty trajectories and child and mother well-being outcomes in Ireland: findings from an Irish prospective cohort 爱尔兰的贫困轨迹与儿童和母亲的幸福结果:爱尔兰前瞻性队列的研究结果
Pub Date : 2024-04-30 DOI: 10.1136/jech-2023-221794
David JO Driscoll, Elizabeth Kiely, Linda M O'Keeffe, Ali S Khashan
Background Poverty is associated with poor outcomes, yet exposure to distinct poverty trajectories in early childhood is not well understood. Objective To understand the prevalence of different trajectories of household poverty and their association with mid-childhood and mother indicators of physical health and psychopathology in Ireland. Methods We used a nationally representative, prospective cohort (Growing Up in Ireland–Infant Cohort). Household poverty included lowest third income decile, subjective poverty and material deprivation when children were aged 9 months, and 3, 5, 9 years. We used group-based multitrajectory cluster modelling to classify trajectories of poverty. Using multivariable logistic regression, adjusted with separate child and mother confounders, we assessed the association of poverty trajectories from 9 months to 9 years with child outcomes (overweight, any longstanding illness and psychopathology) at age 9 years and the same poverty trajectories over the same 9-year period with mother outcomes (overweight, any longstanding illness and depression). Results Of 11 134 participants, 4 trajectories were identified: never in poverty (43.1%), material/subjective>monetary poverty (16.1%), monetary>material poverty (25.6%) and persistent poverty (15.2%). Children in persistent poverty compared with those in never in poverty experienced higher odds of being overweight at 9 years (adjusted OR (aOR) 1.70, 95% CI 1.34, 2.16), having a longstanding illness (aOR 1.51, 95% CI 1.20, 1.91), and psychopathology (aOR 2.06, 95% CI 1.42, 2.99). The outcomes for primary parents (99.7% were mothers) were as follows: having higher odds of being overweight (aOR 1.49, 95% CI 1.16, 1.92), having a longstanding illness (aOR 2.13, 95% CI 1.63, 2.79), and depression (aOR 3.54, 95% CI 2.54, 4.94). Conclusions Any poverty trajectory was associated with poorer psychopathology and physical well-being in late childhood for children and their mothers in Ireland. Data may be obtained from a third party and are not publicly available. The authors received approval from the Central Statistics Office to use the AMF Infant Cohort dataset.
背景 贫困与不良后果相关,但人们对幼儿期不同的贫困轨迹并不十分了解。目标 了解爱尔兰不同家庭贫困轨迹的发生率及其与儿童中期和母亲身体健康和心理病理学指标的关系。方法 我们使用了一个具有全国代表性的前瞻性队列(在爱尔兰成长-婴儿队列)。家庭贫困包括儿童 9 个月、3、5、9 岁时的最低收入十分位数、主观贫困和物质匮乏。我们采用基于群体的多轨迹聚类模型对贫困轨迹进行分类。通过使用多变量逻辑回归,并分别对儿童和母亲的混杂因素进行调整,我们评估了 9 个月至 9 岁期间的贫困轨迹与儿童 9 岁时的结果(超重、任何长期疾病和精神病理学)之间的关系,以及 9 年期间的相同贫困轨迹与母亲的结果(超重、任何长期疾病和抑郁)之间的关系。结果 在 11 134 名参与者中,发现了 4 种贫困轨迹:从未贫困(43.1%)、物质/主观贫困>货币贫困(16.1%)、货币贫困>物质贫困(25.6%)和持续贫困(15.2%)。与从未陷入贫困的儿童相比,持续贫困的儿童在 9 岁时超重(调整 OR (aOR) 1.70,95% CI 1.34,2.16)、长期患病(aOR 1.51,95% CI 1.20,1.91)和心理变态(aOR 2.06,95% CI 1.42,2.99)的几率更高。主要父母(99.7% 为母亲)的结果如下:超重(aOR 1.49,95% CI 1.16,1.92)、长期患病(aOR 2.13,95% CI 1.63,2.79)和抑郁(aOR 3.54,95% CI 2.54,4.94)的几率更高。结论 任何贫困轨迹都与爱尔兰儿童及其母亲童年晚期较差的心理病理学和身体健康有关。数据可能来自第三方,不对外公开。作者使用AMF婴儿队列数据集获得了中央统计局的批准。
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引用次数: 0
Risk of severe mood and anxiety disorders in the adult children of parents with alcohol use disorder: a nationwide cohort study 父母酗酒的成年子女患严重情绪和焦虑症的风险:一项全国性队列研究
Pub Date : 2024-04-30 DOI: 10.1136/jech-2023-221720
Kimberly Kane, Jeanette Westman, Johan Franck, Mika Gissler
Background Growing up with parental alcohol use disorder (AUD) is a risk factor for psychiatric disorders. This study investigated the risk of mood disorders and of anxiety disorders in the adult children of parents with AUD, adjusted for sociodemographic factors. Methods Individual-level register data on the total population were linked to follow children of parents with AUD from 1973 to 2018 to assess their risk of mood disorders and of anxiety disorders. AUD, mood disorders and anxiety disorders were defined with International Statistical Classification of Diseases and Related Health Problems codes from the National Patient Register. HRs of outcomes were calculated with Cox regression. Model 1 was adjusted for the child’s sex, parental education and death of a parent. Model 2 was adjusted for those factors and parental diagnosis of mood or anxiety disorder. Results Those with ≥1 parent with AUD (99 723 of 2 421 479 children) had a higher risk of mood disorder and of anxiety disorder than those whose parents did not have AUD (HR mood 2.32, 95% CI 2.26 to 2.39; HR anxiety 2.66, 95% CI 2.60 to 2.72). The risk remained elevated after adjustment for sociodemographic factors and parental psychiatric diagnosis (HR mood 1.67, 95% CI 1.63 to 1.72; HR anxiety 1.74, 95% CI 1.69 to 1.78). The highest risks were associated with AUD in both parents, followed by AUD in mothers and then in fathers. Conclusion Adult children of parents with AUD have a raised risk of mood and anxiety disorders even after adjustment for sociodemographic factors and parental mood or anxiety disorder. These population-level findings can inform future policies and interventions. Data may be obtained from a third party and are not publicly available. Because of current data protection legislation, the study data cannot be publicly shared. For access to similar study data, contact Statistics Sweden and the Swedish National Board of Health and Welfare, the public authorities that hold the data.
背景 在父母酗酒(AUD)的环境中长大是导致精神障碍的一个危险因素。本研究调查了父母有 AUD 的成年子女患情绪障碍和焦虑症的风险,并对社会人口学因素进行了调整。方法 将总人口的个人层面登记数据与 1973 年至 2018 年期间父母患有 AUD 的子女的情况联系起来,以评估他们罹患情绪障碍和焦虑症的风险。AUD、情绪障碍和焦虑症是根据全国患者登记册中的《疾病和相关健康问题国际统计分类》代码定义的。结果的 HRs 采用 Cox 回归进行计算。模型 1 对儿童性别、父母教育程度和父母死亡进行了调整。模型 2 对这些因素和父母的情绪或焦虑症诊断进行了调整。结果 父母中≥1人患有AUD的儿童(2 421 479名儿童中的99 723人)比父母未患有AUD的儿童患情绪障碍和焦虑障碍的风险更高(情绪HR为2.32,95% CI为2.26至2.39;焦虑HR为2.66,95% CI为2.60至2.72)。在对社会人口因素和父母的精神病诊断进行调整后,该风险仍然较高(情绪 HR 1.67,95% CI 1.63 至 1.72;焦虑 HR 1.74,95% CI 1.69 至 1.78)。父母双方均患有 AUD 的风险最高,其次是母亲患有 AUD,然后是父亲患有 AUD。结论 即使对社会人口因素和父母的情绪或焦虑障碍进行了调整,父母患有 AUD 的成年子女罹患情绪和焦虑障碍的风险仍然较高。这些人群层面的研究结果可为未来的政策和干预措施提供参考。数据可能来自第三方,不对外公开。由于现行的数据保护法规,研究数据不能公开共享。如需获取类似的研究数据,请联系瑞典统计局和瑞典国家卫生与福利局,它们是掌握这些数据的公共机构。
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引用次数: 0
Flourishing and the scope of medicine and public health 繁荣与医学和公共卫生的范围
Pub Date : 2024-04-16 DOI: 10.1136/jech-2023-220553
Tyler J VanderWeele
A framework is put forward for the proper scope of considerations concerning flourishing within medicine, psychiatry, clinical counselling, public health and public policy. Each of these disciplines and associated institutional practices have distinctive contributions to make in advancing flourishing within society. In each case, there are also various aspects of flourishing that extend beyond each practice’s purview; and yet to restrict attention only to health, narrowly conceived, limits what each of these practices can in fact accomplish. A clearer understanding of what aspects of flourishing do, and do not, lie within the bounds of each discipline and practice has the potential to better enable the pursuit of societal well-being.
本文为医学、精神病学、临床咨询、公共卫生和公共政策中有关繁荣的适当考虑范围提出了一个框架。这些学科和相关的机构实践在促进社会繁荣方面都有独特的贡献。在每种情况下,蓬勃发展的各个方面都超出了每种实践的范围;然而,狭隘地将注意力仅仅局限于健康,就会限制每种实践所能实现的目标。更清楚地了解繁荣的哪些方面属于或不属于每门学科和每项实践的范围,有可能更好地促进对社会福祉的追求。
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引用次数: 0
Inequalities in sexual and reproductive outcomes among women aged 16–24 in England (2012–2019) 英格兰 16-24 岁女性在性与生殖结果方面的不平等(2012-2019 年)
Pub Date : 2024-04-12 DOI: 10.1136/jech-2023-220835
Danielle Solomon, Jo Gibbs, Fiona Burns, Hamish Mohammed, Stephanie J Migchelsen, Caroline A Sabin
Background Women aged 16–24 in England have a high burden of sexual and reproductive morbidity, with particularly poor outcomes among people living in more deprived areas (including racially minoritised populations). This analysis used national data to examine the disparities within sexual and reproductive outcomes among this population and to assess whether the patterns of inequality were consistent across all outcomes. Methods Within this ecological study, univariable and multivariable Poisson regression analyses of neighbourhood-level data from national data sets were carried out to investigate the relationships of deprivation and ethnicity with each of six dependent variables: gonorrhoea and chlamydia testing rates, gonorrhoea and chlamydia test positivity rates, and abortion and repeat abortion rates. Results When comparing Index of Multiple Deprivation (IMD) decile 1 (most deprived) and IMD decile 10 (least deprived), chlamydia (RR 0.65) and gonorrhoea (0.79) testing rates, chlamydia (0.70) and gonorrhoea (0.34) positivity rates, abortion rates (0.45) and repeat abortion rates (0.72) were consistently lower in IMD decile 10 (least deprived). Similarly, chlamydia (RR 1.24) and gonorrhoea positivity rates (1.92) and repeat abortion rates (1.31) were higher among black women than white women. Results were similar when both ethnicity and deprivation were incorporated into multivariable analyses. Conclusion We found similar patterns of outcome inequality across a range of sexual and reproductive outcomes, despite multiple differences in the drivers of each outcome. Our analysis suggests that there are broad structural causes of inequality across sexual and reproductive health that particularly impact the health of deprived and black populations. Data may be obtained from a third party and are not publicly available. Data used in this analysis are held by the Department of Health and Social Care and the UK Health Security Agency, and as such are not publicly available.
背景 英国 16-24 岁女性的性疾病和生殖疾病发病率较高,生活在较贫困地区的人群(包括少数种族人群)的发病率尤其高。本分析使用全国性数据来研究这一人群在性和生殖结果方面的差异,并评估所有结果的不平等模式是否一致。方法 在这项生态学研究中,对全国数据集中的邻近地区数据进行了单变量和多变量泊松回归分析,以研究贫困和种族与以下六个因变量之间的关系:淋病和衣原体检测率、淋病和衣原体检测阳性率、人工流产率和重复人工流产率。结果 比较多重贫困指数第 1 十分位数(最贫困)和第 10 十分位数(最不贫困),衣原体(RR 0.65)和淋病(0.79)检测率、衣原体(0.70)和淋病(0.34)阳性率、人工流产率(0.45)和重复人工流产率(0.72)在多重贫困指数第 10 十分位数(最不贫困)一直较低。同样,黑人妇女的衣原体阳性率(RR 1.24)、淋病阳性率(1.92)和重复流产率(1.31)均高于白人妇女。如果将种族和贫困程度纳入多变量分析,结果也类似。结论 我们发现,尽管每种结果的驱动因素存在多种差异,但在一系列性和生殖结果中,结果不平等的模式相似。我们的分析表明,造成性健康和生殖健康不平等的广泛结构性原因尤其影响了贫困人口和黑人的健康。数据可能来自第三方,不对外公开。本分析中使用的数据由英国卫生与社会关怀部和英国卫生安全局掌握,因此不对外公开。
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引用次数: 0
SARS-CoV-2 vaccine uptake and risks of severe COVID-19 disease among people prescribed opioid agonist therapy in Scotland 苏格兰接受阿片类受体激动剂治疗者的 SARS-CoV-2 疫苗接种率和严重 COVID-19 疾病风险
Pub Date : 2024-04-09 DOI: 10.1136/jech-2023-221602
Alan Yeung, Max Wilkinson, Jen Bishop, Bob Taylor, Norah Palmateer, Lee Barnsdale, Jaroslaw Lang, Claire Cameron, Duncan McCormick, Tracey Clusker, Andrew McAuley, Sharon Hutchinson
Background There is limited evidence quantifying the risk of severe COVID-19 disease among people with opioid dependence. We examined vaccine uptake and severe disease (admission to critical care or death with COVID-19) among individuals prescribed opioid agonist therapy (OAT). Method A case–control design was used to examine vaccine uptake in those prescribed OAT compared with the general population, and the association between severe disease and OAT. In both analyses, 10 controls from the general population were matched (to each OAT recipient and COVID-19 case, respectively) according to socio-demographic factors. Conditional logistic regression was used to estimate rate ratios (RR) for severe disease. Results Vaccine uptake was markedly lower in the OAT cohort (dose 1: 67%, dose 2: 53% and dose 3: 31%) compared with matched controls (76%, 72% and 57%, respectively). Those prescribed OAT within the last 5 years, compared with those not prescribed, had increased risk of severe COVID-19 (RR 3.38, 95% CI 2.75 to 4.15), particularly in the fourth wave (RR 6.58, 95% CI 4.20 to 10.32); adjustment for comorbidity and vaccine status attenuated this risk (adjusted RR (aRR) 2.43, 95% CI 1.95 to 3.02; wave 4 aRR 3.78, 95% CI 2.30 to 6.20). Increased risk was also observed for those prescribed OAT previously (>3 months ago) compared with recently (aRR 1.74, 95% CI 1.11 to 2.71). Conclusions The widening gap in vaccine coverage for those prescribed OAT, compared with the general population, is likely to have exacerbated the risk of severe COVID-19 in this population over the pandemic. However, continued OAT use may have provided protection from severe COVID-19 among those with opioid dependence. Data may be obtained from a third party and are not publicly available. Access to the individual level data can be sought through approval of the Public Benefit and Privacy Panel for Health and Social Care ([www.informationgovernance.scot.nhs.uk/pbpphsc/home/for-applicants/][1]). [1]: http://www.informationgovernance.scot.nhs.uk/pbpphsc/home/for-applicants/
背景 对阿片类药物依赖者患严重 COVID-19 疾病的风险进行量化的证据有限。我们研究了阿片类药物激动剂疗法(OAT)处方者的疫苗接种率和严重疾病(因 COVID-19 而入院接受重症监护或死亡)发生率。方法 我们采用了病例对照设计来研究与普通人群相比,OAT处方者的疫苗接种率,以及严重疾病与OAT之间的关联。在这两项分析中,根据社会人口因素从普通人群中挑选了 10 名对照组(分别与 OAT 接种者和 COVID-19 病例匹配)。条件逻辑回归用于估计严重疾病的比率(RR)。结果 与匹配对照组(分别为 76%、72% 和 57%)相比,OAT 组群的疫苗接种率明显较低(第一剂:67%;第二剂:53%;第三剂:31%)。与未服用 OAT 的人群相比,在过去 5 年中服用过 OAT 的人群发生严重 COVID-19 的风险增加(RR 3.38,95% CI 2.75 至 4.15),尤其是在第四波(RR 6.58,95% CI 4.20 至 10.32);对合并症和疫苗接种状况进行调整后,这一风险有所降低(调整后 RR (aRR) 2.43,95% CI 1.95 至 3.02;第四波 aRR 3.78,95% CI 2.30 至 6.20)。以前(>3 个月前)开过 OAT 处方的人与最近开过 OAT 处方的人相比,风险也有所增加(aRR 1.74,95% CI 1.11 至 2.71)。结论 与普通人群相比,开具 OAT 的人群在疫苗覆盖率方面的差距不断扩大,这很可能加剧了这一人群在大流行期间罹患严重 COVID-19 的风险。不过,继续使用 OAT 可能会保护阿片类药物依赖者免受严重 COVID-19 的感染。数据可能来自第三方,不对外公开。个人层面的数据可通过卫生与社会保健公共利益与隐私小组([www.informationgovernance.scot.nhs.uk/pbpphsc/home/for-applicants/][1])的批准获取。[1]: http://www.informationgovernance.scot.nhs.uk/pbpphsc/home/for-applicants/
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引用次数: 0
Long echo of sociopolitical upheaval: life events and health in East Germany 社会政治动荡的长久回响:东德的生活事件与健康
Pub Date : 2024-04-08 DOI: 10.1136/jech-2024-221974
Nico Dragano, Domantas Jasilionis
Major sociopolitical upheavals change the course of history. However, this is not to be understood abstractly. The effects of wars, crises, sociopolitical change and technical or cultural innovations are felt first-hand by people in their everyday lives. Numerous findings suggest that social determinants have a lasting impact on the health of individuals and entire societies.1 2 Sociopolitical upheavals are nothing other than a fundamental reorganisation of these determinants—often in a relatively short period—and as such, they are an important subject of epidemiology. One of the fundamental political and social upheavals of recent decades was the collapse of the USSR (Union of Soviet Socialist Republics), which took place gradually from the mid-1980s onwards, reaching a dramatic climax in the early 1990s and whose long-term effects are still being felt today. This world-historical event had some drastic consequences for the population health in the countries primarily affected—both positive and negative.3–5 The article by Hahm et al attempts to build a bridge between …
重大的社会政治动荡会改变历史进程。然而,我们不能抽象地理解这一点。战争、危机、社会政治变革以及技术或文化创新的影响,人们在日常生活中都能亲身感受到。大量研究结果表明,社会决定因素对个人和整个社会的健康有着持久的影响。1 2 社会政治动荡无非是这些决定因素的根本性重组--往往是在相对较短的时间内--因此,它们是流行病学的一个重要课题。苏联(苏维埃社会主义共和国联盟)的解体是近几十年来最根本的政治和社会动荡之一,这一动荡从 20 世纪 80 年代中期开始逐渐发展,在 20 世纪 90 年代初达到了戏剧性的高潮,其长期影响至今仍在显现。这一世界历史性事件对主要受影响国家的人口健康产生了一些严重后果--既有积极的,也有消极的。
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引用次数: 0
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Journal of Epidemiology & Community Health
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