Evaluating Extracorporeal Membrane Oxygenation and Ventilation Treatment of Patients with COVID-19: A Review

Habib Hybar, A. Samimi, M. Maniati, Javad Jodat, Zahra Gatavizadeh
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Abstract

The prevalence of COVID-19 in the world is rapidly increasing. Although some patients show mild symptoms of the virus, some others need special care due to the exacerbation of the disease. Therefore, invasive treatments are needed to treat these patients. Data were collected from PubMed and Google scholars at various time points up to the 2020 academic year. The related keywords are listed as follows: "COVID-19", "Treatment", "Pathogenesis", and "Lung disorder". Studies have shown that although the use of ECMO and ventilation can provide oxygen to patients and improve their clinical status; these procedures can lead to the activation of inflammatory responses and the activation of the renin-angiotensin system. Inflammation and activation of the renin-angiotensin system are among the weak prognoses for COVID-19-infected patients. ECMO and ventilation treatment procedures are like double-edged swords, and monitoring patients during treatment is essential to prevent renin-angiotensin activation. *Corresponding Author: Zahra Gatavizadeh; Email: z-gatavizadeh@ajums.ac.ir Please cite this article as: Hybar H, Samimi A, Maniati M, Jodat J, Gatavizadeh Z. Evaluating Extracorporeal Membrane Oxygenation and Ventilation Treatment of Patients with COVID-19: A Review. Arch Med Lab Sci. 2020;6:1-6 (e16). https://doi.org/10.22037/amls.v6.33550
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体外膜氧合和通气治疗COVID-19的研究进展
COVID-19在世界范围内的流行率正在迅速上升。虽然一些患者表现出轻微的病毒症状,但由于疾病的恶化,其他一些患者需要特别护理。因此,需要对这些患者进行侵入性治疗。数据是在2020学年之前的不同时间点从PubMed和谷歌学者那里收集的。相关关键词如下:“COVID-19”、“治疗”、“发病机制”、“肺部疾病”。研究表明,虽然使用ECMO和通气可以为患者提供氧气,改善其临床状况;这些过程可导致炎症反应的激活和肾素-血管紧张素系统的激活。感染covid -19的患者预后不佳的因素包括炎症和肾素-血管紧张素系统的激活。ECMO和通气治疗过程就像一把双刃剑,在治疗过程中对患者进行监测对于防止肾素-血管紧张素激活至关重要。*通讯作者:Zahra Gatavizadeh;Hybar H, Samimi A, Maniati M, Jodat J, Gatavizadeh Z.体外膜氧合和通气治疗新冠肺炎的研究进展中华医学杂志,2020;6:1-6 (e16)。https://doi.org/10.22037/amls.v6.33550
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