Kaze Paul Davou, I. Lawal, Ajanusi Joseph, S. Lawal, Karaye Gp, M. Patrobas, B. Markus, F. Ayinzat, D. Christopher, K. Karaye
{"title":"T Lymphocytes Response to Caecal Coccidiosis in Broilers Infected with Exo and Endogenous Stages of Eimeria Tenella","authors":"Kaze Paul Davou, I. Lawal, Ajanusi Joseph, S. Lawal, Karaye Gp, M. Patrobas, B. Markus, F. Ayinzat, D. Christopher, K. Karaye","doi":"10.15226/2372-0948/6/1/00166","DOIUrl":null,"url":null,"abstract":"The present study reveals the proliferation of cytokines in treated and non- treated broilers consisting of IFN- γ, IL-1, IL-2, IL-4, IL-6, TNF and TGF. The CD4 count in the treated and non- treated broilers orally administered with various developmental stages of the parasite reached a peak on day 10 at primary; secondary and day 24 at tertiary infections. There was significant difference in the CD4 cell count between groups of the infected broiler chickens (p < 0.05). The current study observed a relationship between the different developmental stages of the parasite and lymphocytes response. Broiler chickens infected with sporulated oocyst (sporozoites) and merozoites treated and non-treated gave high CD4 T- lymphocyte numbers than the other groups throughout the experimental periods.","PeriodicalId":90344,"journal":{"name":"SOJ immunology","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2018-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"3","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"SOJ immunology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.15226/2372-0948/6/1/00166","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 3
Abstract
The present study reveals the proliferation of cytokines in treated and non- treated broilers consisting of IFN- γ, IL-1, IL-2, IL-4, IL-6, TNF and TGF. The CD4 count in the treated and non- treated broilers orally administered with various developmental stages of the parasite reached a peak on day 10 at primary; secondary and day 24 at tertiary infections. There was significant difference in the CD4 cell count between groups of the infected broiler chickens (p < 0.05). The current study observed a relationship between the different developmental stages of the parasite and lymphocytes response. Broiler chickens infected with sporulated oocyst (sporozoites) and merozoites treated and non-treated gave high CD4 T- lymphocyte numbers than the other groups throughout the experimental periods.