Perspectives Concerning SARS-CoV-2 Transmission for the Application of the Livestock Breeding

T. Pasharawipas
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Abstract

Viral transmission between animals and humans has been defined as Zoonosis and zooanthroponosis. The vaccine has been claimed to be the best tool to prevent viral epidemics. However, as learned from SARSCoV-2, vaccines cannot be the true answer to prevent viral infection for everyone. Some vaccinated persons are still reported to get infected. Viral mutation has been principally postulated to explain immune evasion. Questionable, why the mutated viral strain does not evade the immunity of everyone who has been vaccinated? Mutated viral strains cause various symptoms, nonsymptomatic to morbidity and mortality, in different individuals with more or less the same ratio as the original SARS-CoV-2. Approximately, 25-35% of the SARSCoV-2 detected individuals are asymptomatic, while 15- 20% developed severity and about 2-5% have critical symptoms [1,2]. Logically, the viral mutation could keep mutating in any part of its genome. The new variant might maintain infectivity in the same person and might develop to infect another person who once has not been susceptible to the original strain. Thus, the dynamics of viral infection could change from time to time. This requires a better explanation to lead us in the right direction to prevent the emergent virus either now or in the future.
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SARS-CoV-2传播在畜牧养殖中的应用展望
动物与人类之间的病毒传播被定义为人畜共患病和人畜共患病。这种疫苗被认为是预防病毒流行的最佳工具。然而,从SARSCoV-2中学到,疫苗并不是预防所有人感染病毒的真正答案。据报道,一些接种过疫苗的人仍然受到感染。病毒突变主要被假定为免疫逃避的原因。值得怀疑的是,为什么变异的病毒株不能逃避所有接种过疫苗的人的免疫?变异的病毒株在不同个体中引起各种症状,从无症状到发病率和死亡率,其比例与原始SARS-CoV-2大致相同。大约25-35%的SARSCoV-2检测个体无症状,而15- 20%发展为严重症状,约2-5%有严重症状[1,2]。从逻辑上讲,病毒突变可以在其基因组的任何部分持续突变。新的变种可能在同一个人身上保持传染性,并可能发展到感染另一个曾经对原始菌株不敏感的人。因此,病毒感染的动态可能会不时发生变化。这需要一个更好的解释来引导我们朝着正确的方向前进,以防止现在或将来出现的病毒。
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